The African swine fever vaccine will enter expanded clinical and productive trials

BEIJING, Aug. 18 (Xinhua) -- The African
vaccine independently developed by china's Agriculture
Harbin Veterinary Research Institute is progressing smoothly, and on the basis of the preliminary completion of laboratory and intermediate trial phase studies of candidate vaccine strains, the vaccine environmental release trials have been completed and are about to enter the stage of expanding clinical trials and productive trials, the Ministry of Agriculture and Rural Affairs said in a news release.
According to The Director of Harbin Veterinary Research Institute, Step Zhigao, in the environmental release trial phase, the vaccine will be 10 times and 100 times the dose of immunization to inoculated commercial fattening piglets, sows, continuous observation for 20 weeks, inoculated pigs are not significantly elevated body temperature and other clinical abnormal symptoms and pathological damage. Commodity fattening piglets grow and develop well after vaccination, no vaccine virus emissions and horizontal transmission phenomenon. Sows normal hair, breeding, no abortion occurred, pregnant sows after vaccination no abortion occurred, are normal delivery, no vertical transmission was observed, the production of piglets growth and development in good condition.
National Agriculture
Tang Huajun said that with the approval of the Ministry of Agriculture and Rural Affairs, ha animal research in early April, early May and early June in Heilongjiang, Henan and Xinjiang, respectively, three bases carried out clinical trials of vaccines, a total of nearly 3000 commercial fattening pigs. Up to now, the growth status of immune pigs is good, no obvious adverse clinical reactions, no obvious pathological changes in immune pig cesarean section, no vaccine toxic discharge, no horizontal transmission, immune pigs in high-grade biosecurity laboratory with strong poison, different doses of immunization group immunization protection rate of more than 80%.
Next, China Agriculture
will continue to follow the work of the Ministry of Agriculture and Rural Affairs, accelerate the promotion of vaccine production trial research, further expand the scope of clinical trials in Heilongjiang and other places, and strive to complete the relevant trials at an early stage, in accordance with the legal procedures to enter the safety certificate declaration and vaccine registration process.