The antitumor mechanism of ganoderma polysaccharide has been elucidated

2013-09-05 classification: efficacy effect: 0 people commented that many people know that ganoderma polysaccharide has the effect of strengthening immunity and anti-cancer In order to solve the key reasons, Wu Zongyi, deputy researcher of genetics center of Academia Sinica in Taiwan, led the team to take the lead in solving the mechanism of Ganoderma Polysaccharide's anti-cancer action It was confirmed by experiments that the key lies in one of the Ganoderma polysaccharides called fucose "Can induce antibodies and then kill cancer cells, thus solving the mystery The research has been published in the latest issue of the proceedings of the National Academy of Sciences Scientists from all over the world have invested more than 100 years in the study of the efficacy of Ganoderma lucidum polysaccharides Although there have been many papers on the efficacy of Ganoderma lucidum in the past, this is the first time to find out its mechanism Wu said the results showed that three weeks after the mice received F3 injection at a dose of 240 mg / kg, the tumor cells shrank to a quarter of their original size Previously, the research team of Professor Xu Xianye from Yangming University in Taiwan, China, has found that F3 can effectively inhibit the growth of tumor when it is injected into mice that produce lung cancer, but its anti-cancer mechanism has not been effectively explained by using known immunology knowledge The key point of the experiment is that fucose, a component of ganoderma polysaccharide, can induce more antibodies against Globo h, and inhibit the growth of tumor more effectively The result shows that fucose is the key of ganoderma polysaccharide to fight cancer If fucose is removed, its activity will be greatly reduced The research results are published in the latest issue of PNAs and have been specially written The ultimate goal of Professor Xu Xianye's research team is to find and analyze the minimum molecular structure of anti-cancer components of Ganoderma lucidum polysaccharides If this goal can be successfully achieved, anti-cancer drugs can be produced by chemical synthesis.