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    Home > Biochemistry News > Biotechnology News > The bifunctional fusion protein targeting PD-L1/TGF-β was approved by the FDA

    The bifunctional fusion protein targeting PD-L1/TGF-β was approved by the FDA

    • Last Update: 2021-06-16
    • Source: Internet
    • Author: User
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    Article source: Pharmaceutical Guanlan

    On June 2nd, Boji Biomedical Technology (Hangzhou) Co.


    BJ-005 is a recombinant dual-function fusion of a humanized anti-programmed death ligand 1 (PD-L1) IgG1 monoclonal antibody and a part of the extracellular domain of human transforming growth factor β (TGF-β) receptor II The fusion protein can simultaneously target PD-L1 and TGF-β, inhibit tumor growth by targeting immune checkpoints and regulating tumor cell growth cytokine pathways, and is used to treat cancer patients


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