The biological clock is out of time?

But a new study by the University of Colorado at Boulder, funded by the U.

"This study shows that by promoting and stabilizing the beneficial bacteria in the gut and the metabolites it releases, we may be able to make our bodies more resilient to respond to circadian interruptions," said Monica Monica, professor of integrated physiology and senior author.

This animal study, published in the journal Brain, Behavior and Immunity, is the latest to show that prebiotics (not to be confused with the probiotics in fermented foods such as yogurt and sauerkraut) not only affect the intestines, It also affects brain and behavior research

In breast milk, these indigestible carbohydrates are naturally rich in many fiber foods, including leeks, artichokes, and onions.

The author’s previous research has shown that rats grown up on prebiotic-infused food sleep better and are more resilient to some of the physiological effects of acute stress

In the new study, part of a multi-university project funded by the U.

"They travel all over the world and often change time zones

How a healthy gut can prevent jet lag

Researchers fed rats with common food or food rich in two prebiotics, galactooligosaccharide and polydextrose

Then, they controlled the rat's day and night cycle for 8 consecutive weeks-equivalent to arriving at a time zone 12 hours earlier each week for 2 months

Mice that eat prebiotics can adjust their sleep-wake cycle and core body temperature faster (when the internal clock is turned off, the core body temperature will also be disrupted), and resist changes in the intestinal flora that usually accompany stress

Thompson said: "This is one of the first studies linking prebiotic intake to specific bacterial changes that not only affect sleep, but also affect the body's response to interrupted circadian rhythms

This research also takes a crucial step in answering the following question: How does the simple intake of starch affect our sleep and feeling?

Researchers have found that those who eat a prebiotic diet have a large number of several health-promoting microorganisms, including Ruminiclostridium 5 (shown in other studies to reduce fragmented sleep) and Parabacteroides disasonis

They also have an essentially different "metabolome", which is a collection of metabolic byproducts produced by gut bacteria

In short: animals that consume prebiotics have more beneficial bacteria in their bodies, and these beneficial bacteria produce metabolites to protect them from jet lag

Is the supplement valuable?

The University of Colorado at Boulder is conducting clinical trials to determine whether prebiotics will have similar effects in humans

This research may design customized pre-life mixtures for people whose occupations or life>

At the same time, can eating more beans and other foods rich in natural compounds keep your biological clock running on time? They say that this is not impossible, but unlikely
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They pointed out that, in human terms, rats were fed an excessive amount of prebiotics
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Why not ingest beneficial bacteria directly through foods rich in probiotics such as yogurt?

This may also help, but prebiotics may have an advantage over probiotics because they support the beneficial bacteria we already have, rather than introducing a new species that may or may not dominate
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What about prebiotic dietary supplements?

"If you are happy, healthy, and balanced, you don't need to eat a lot of things that contain prebiotics," Fleshner said
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"But if you know that you are facing challenges, you can look at some of the available prebiotics
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You have to know that they are not customized yet, so it may be useful to you, but it is useless to your neighbors
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"

Journal Reference :

1. Robert S.
   Thompson, Michelle Gaffney, Shelby Hopkins, Tel Kelley, Antonio Gonzalez, Samuel J.
   Bowers, Martha Hotz Vitaterna, Fred W.
   Turek, Christine L.
   Foxx, Christopher A.
   Lowry, Fernando Vargas, Pieter C.
   Dorrestein, Kenneth P.
   Wright, Rob Knight, Monika Fleshner.
   Ruminiclostridium 5, Parabacteroides distasonis, and bile acid profile are modulated by prebiotic diet and associate with facilitated sleep/clock realignment after chronic disruption of rhythms .
   Brain, Behavior, and Immunity , 2021; 97: 150 DOI: 10.
   1016/j.
   bbi.
   2021.
   07.
   006