Sleep disordered breathing (SDB) is very common after stroke
.
About two-thirds of stroke patients have varying degrees of SDB, and up to two-fifths of post-stroke delays (≥3 months) have apnea-hypopnea index (AHI) higher than 20 beats/hour
.
A study in Thorax describes the clinical and ventilatory sensitivity of SDB (obstructive, central sleep apnea, coexisting central and obstructive sleep apnea (coexisting sleep apnea)) at least 3 months after the first ischemic stroke Sexual characteristics
.
.
About two-thirds of stroke patients have varying degrees of SDB, and up to two-fifths of post-stroke delays (≥3 months) have apnea-hypopnea index (AHI) higher than 20 beats/hour
.
A study in Thorax describes the clinical and ventilatory sensitivity of SDB (obstructive, central sleep apnea, coexisting central and obstructive sleep apnea (coexisting sleep apnea)) at least 3 months after the first ischemic stroke Sexual characteristics
.
Stroke Thorax
A prospective, single-center cohort cross-sectional study was conducted in a university hospital
.
From December 2016 to December 2019, 380 patients with continuous stroke or transient ischemic attack were screened
.
The median time after stroke onset was 134.
5 (97.
0; 227.
3) days.
Polysomnography and hyperventilation response were performed overnight
.
The monitored parameters include electroencephalogram, electrooculogram, submental electromyogram, tibial electromyogram, ECG
.
Nocturnal blood oxygen saturation measurements
.
.
From December 2016 to December 2019, 380 patients with continuous stroke or transient ischemic attack were screened
.
The median time after screening for stroke onset was 134.
5 (97.
0; 227.
3) days, and polysomnography and hyperventilation responses were performed throughout the night
.
The monitored parameters include electroencephalogram, electrooculogram, submental electromyogram, tibial electromyogram, ECG
.
Nocturnal blood oxygen saturation measurements
.
185 first-time stroke patients were included in the analysis
.
94 patients (50.
8%) had no SDB or only mild SDB (apnea-hypopnea index <15 beats/hour), 91 patients (49.
2%) had moderate to severe SDB, of which 52 patients (57.
1%) were obstructive Sleep apnea, 39 cases (42.
9%) were coexistent or central sleep apnea
.
The clinical manifestations of patients with obstructive sleep apnea are significantly different from those with no SDB or with mild SDB, but there is no difference from patients with coexisting and central sleep apnea
.
Compared with patients with no SDB or mild SDB, the latter showed higher cerebellar damage and hyperventilation response
.
.
94 patients (50.
8%) had no SDB or only mild SDB (apnea-hypopnea index <15 beats/hour), 91 patients (49.
2%) had moderate to severe SDB, of which 52 patients (57.
1%) were obstructive Sleep apnea, 39 cases (42.
9%) were coexistent or central sleep apnea
.
The clinical manifestations of patients with obstructive sleep apnea are significantly different from those with no SDB or with mild SDB, but there is no difference from patients with coexisting and central sleep apnea
.
Compared with patients with no SDB or mild SDB, the latter showed higher cerebellar damage and hyperventilation response
.
94 patients (50.
8%) had no SDB or only mild SDB (apnea-hypopnea index <15 beats/hour), 91 patients (49.
2%) had moderate to severe SDB, of which 52 patients (57.
1%) were obstructive Sleep apnea, 39 cases (42.
9%) were coexistent or central sleep apnea
.
Compared with patients with no SDB or mild SDB, the latter showed higher cerebellar damage and hyperventilation response
.
The results showed that the performance of SDB in first-time stroke patients was different due to their respective clinical characteristics and ventilation sensitivity characteristics
.
The increased hypercapnic ventilatory response of patients with coexistence and central sleep apnea stroke may lead to specific ventilatory support
.
.
The increased hypercapnic ventilatory response of patients with coexistence and central sleep apnea stroke may lead to specific ventilatory support
.
Original source:
Original source:Sébastien Baillieul, Sébastien Bailly, et al, S leep- disordered breathing and ventilatory chemosensitivity in first ischaemic stroke patients: a prospective cohort study , thorax, 2021, http://dx.
doi.
org/10.
1136/thoraxjnl-2021-218003.
doi.
org/10.
1136/thoraxjnl-2021-218003.
leep- disordered breathing and ventilatory chemosensitivity in first ischaemic stroke patients: a prospective cohort study
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