The collaborative research of Yu Yongfu's research group of Fudan University has made progress in the field of diabetes

Recently, the research group of Yongfu Yu of the School of Public Health of Fudan University, the research group of Professor Xi Bo of the School of Public Health of Shandong University and Professor Jiong Li of Aarhus University in Denmark have made progress in the field of childhood diabetes and early-onset kidney disease, and the paper "Childhood diabetes mellitus and early-onset kidney diseases later in life: a nationwide.
" population-based matched cohort study" was published in BMC Medicine in November 2022
.

Diabetes is one of the leading chronic diseases in children and adolescents, and the prevalence of childhood diabetes is rising globally, making it a major global public health problem
.
Studies have suggested that childhood diabetes may be associated with early-onset kidney disease, but there are no clear conclusions due to study design, and little is known about the effects of childhood diabetes types (type 1 diabetes and type 2 diabetes) on specific types of kidney disease
.

To explore the relationship between childhood diabetes and overall and specific types of early-onset kidney disease, Yu's team conducted a cohort study
based on a large sample population.
The study found that children with diabetes had a 154% increased risk of developing early-onset kidney disease, with 148% and 175% increased risk associated with type 1 diabetes and type 2 diabetes, respectively; The study also found an increased risk of several specific types of kidney disease in children with diabetes, including glomerular disease, tubulointerstitial disease, kidney failure, and urolithiasis
.
This study demonstrates that children with diabetes have an increased risk of early onset kidney disease overall and specific types, and that preventing and treating diabetes early in childhood may significantly reduce the risk of
developing kidney disease later in life.

Sun Jiahong, a postdoctoral fellow in the Department of Epidemiology, School of Public Health, Shandong University, and Wang Ce, a doctoral student in the Department of Biostatistics, School of Public Health, Fudan University, are co-first authors of this paper, and Professor Xi Bo of the School of Public Health of Shandong University and Yongfu Yu, a young researcher at the School of Public Health of Fudan University, are co-authors
.
The research was supported by the Shanghai Youth Science and Technology Daystar Program (21QA1401300), the Shanghai Natural Science Foundation (22ZR1414900) and the Shanghai Municipal Science and Technology Major Project (ZD2021CY001
).

Link to the paper: https://bmcmedicine.
biomedcentral.
com/articles/10.
1186/s12916-022-02634-4