The detox function of small molecule citrus pectin.

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is a multi-component mixed drink containing ethanol, which is the main component of alcohol. Under normal circumstances, the human body can only metabolize a certain amount of ethanol, when drinking too much, the amount of ethanol oxidation into acetaldehyde will increase, and the body's decomposition of acetaldehyde is limited in a certain period of time. When the acetaldehyde content is too high, the human body can not break down in time, acetaldehyde into the blood and is absorbed, will lead to serious damage to vital organs and functions of the human body, but also may appear mental excitement, dizziness, vomiting and other discomfort, that is, so-called intoxication. Whether a person is intoxicated or not depends on the concentration of ethanol in the blood. When the concentration of ethanol in the blood is 0.05% to 0.1%, people begin to be hazy and happy slightly drunk, and when they reach 0.3%, people will be mouthless, gait hobbled, that is, usually said drunk. If it reaches 0.7%, people will die.
natural citrus pectin (Citrus Pectin for "CP") hydrolysed product - small molecule citrus pectin ("LCP") can effectively relieve intoxication, the principle of its action is: After taking, the human body can not only form a protective membrane in the gastrointestinal tract to prevent the absorption of alcohol, protect the gastrointestinal tract, but also activate the activity of anti-alcohol enzymes, promote the absorption of alcohol into carbon dioxide and water, play a role in preventing alcohol absorption and promote alcohol decomposition of the double anti-alcohol effect.
ethanol dehydrogenase determines the amount of alcohol
some people drink a drink, some do not drink a thousand glasses, sometimes drink can sweep the winery, sometimes drink a little on the float. The amount of alcohol varies from person to person, but also from state to state, what determines the amount of alcohol? There is a big difference between people and people in the tolerance of ethanol. This is due to the gastrointestinal absorption capacity and the liver's metabolic processing capacity is different, which also results in different amounts of alcohol between people.
alcohol is metabolized in the body in three ways - the liver, skin and respiratory system, about 95% of which are oxidized through the liver's enzyme system. Oxidation metabolism through the liver enzyme system is as follows:
Most human body ethanol dehydrogenase quantity is basically equal, but the activity will change due to changes in individual physiological conditions. There is a small number of people lack of acetaldehyde dehydrogenase, so that acetaldehyde can not be completely broken down into acetic acid, but in the form of acetaldehyde continue to remain in the body, making people drink after nausea, coma and other drunken symptoms. Generally speaking, people who do not drink well or drink less than a reasonable amount of alcohol will have insufficient or complete lack of acetaldehyde dehydrogenase in their bodies. For good drinkers, if drinking too much, too fast, more than acetaldehyde dehydrogenase decomposition capacity, will also occur intoxication. Therefore, the amount of alcohol is mainly determined by the absorption capacity of the stomach to alcohol, the vitality and quantity of ethanol dehydrogenase and acetaldehyde dehydrogenase.
the key to solve the problem of intoxication is how to make the human body's vital organs and central nerves, blood as little contact as possible by ethanol into the human body produced by the toxic substance "acetaldehyde", reduce the oxidation capacity of acetaldehyde to cells. In general, antidumeners can slow the oxidation of ethanol into acetaldehyde, while accelerating the decomposition of acetaldehyde into acetic acid, carbon dioxide and water.
moderate drinking can make people happy, maintain vitality, and in social situations can ease the atmosphere, enhance feelings, have a certain health effect. But drinking a lot of fast alcohol can be very harmful to the body, especially if you drink on an empty stomach. The first harm is the liver, long-term excessive drinking is often accompanied by fatty liver, alcoholic liver, hepatitis and cirrhosis, but also due to the liver detoxification capacity, resulting in low immunity, prone to cancer and other diseases. The second is to hurt the gastrointestinal tract, long-term heavy drinkers will generally have gastritis, stomach ulcers or stomach bleeding experience. In addition to liver and gastrointestinal damage, drinking alcohol can easily lead to high blood pressure and lead to corresponding cardiovascular disease. Some reports suggest that long-term alcoholics tend to have atrophy of the cerebral corty, mental decline, and irritability. In addition, drinking alcohol in pregnant women can cause harm to the developing fetus, such as fetal malformation, stillbirth, growth retardation and behavioral defects. Drinking more than 250mL of ethanol alcohol can easily lead to death.
chinese medicine books or magazines in previous generations recorded in the role of anti-alcohol Chinese medicine, such assub - in the folk have "a thousand cups not drunkson" title.son can solve the diseases such as nausea, thirst and boredicness, windy communication, tongli two, wake up and drink, and treat chest irritability, head wind, thirst and so on caused by excessive drinking. Ginseng's detoxification effect on ethanol is very obvious, it can not only shorten the duration of ethanol anesthesia and speed up the return to normal time, but also reduce the content of GOT, GPT, ALP and bilirbin in the serum, but also increase the activity of alcohol dehydrogenase and aldehyde dehydrogenase related to ethanol metabolism, while the toxic substance acetaldehyde produced by metabolism is quickly excreted, thus effectively protecting the liver of ethanol poisoning. Reishi has a protective effect on a variety of liver damage, whether before or after liver damage, taking Reishi can protect the liver and reduce liver damage. Reishi can also promote the liver's metabolism of poisons, for toxic hepatitis has a definite effect. Reishi can obviously eliminate dizziness, fatigue, nausea, liver discomfort and other symptoms, and can effectively improve liver function.
work should be paid, friends and family gathering, wine has become a lot of social relations intertwined media. In order to effectively protect the body from alcohol, you need to know some drinking tips. First of all, do not drink on an empty stomach, drinking on an empty stomach not only makes people drink less than usual half, more importantly, stomach and liver. If it's too late to eat to fill your stomach, eating two pieces of hard candy or a fruit rich in dietary fiber and VC can protect your liver and gastrointestinal tract. If you have time, it is best to drink a glass of honey water or apple juice with skin, the pectin in the apple skin can form a protective film in the stomach, slowing the absorption of alcohol in the stomach. After drinking, in order to prevent the occurrence of headaches, stomach pain and nausea and vomiting caused by drunken hangovers, you can eat a piece of VB6 after the party, which can promote metabolism, strengthen the speed of detox, and facilitate the regeneration of liver cells, thereby promoting the recovery of liver damage. In addition to VB6, calcium tablets, propolis, tomatoes, pectin powder, sea otters, grapes, grapefruit, pumpkins, sweet potatoes, etc. can slow the occurrence of hangover symptoms.
Small molecule citrus pectin natural anti-alcohol effect
Natural plant anti-alcohol efficacy can not be underestimated, after experiments found that the natural citrus pectin hydrolysis of small molecule citrus pectin can form a protective film in the human gastrointestinal tract and can enter the blood to promote alcohol decomposition.
Natural Citrus pectin is a polysaccharide complex extracted from the peels and flesh of citrus, lemon, orange, grapefruit, and its molecules are present in a long-chain carbohydrate structure, its molecular structure is shown on the left.
The molecular weight of pectin extracted directly from citrus peel is about 5 to 300,000, the esterification degree is 65% to 73%, the main components are methyl esterified alpha (1.4)-D-polysaccharide acid and a small amount of Arabic sugar and polyester sugar. Natural citrus pectin is generally used as an additive in the food industry, and has good gel, stability, emulsification, thickening and suspension function. Pectin is also pure natural water-soluble dietary fiber without any toxic side effects, has a very important position in healthy food, has gradually begun to be recognized and applied.
natural pectin can not be absorbed by the intestines after consumption, only in the gastrointestinal role, beneficial to the body but its function is limited to the digestive system. And a new modified citrus pectin, can be absorbed by the gastrointestinal tract into the blood circulation, dietary fiber can enter the blood circulation, which will be a qualitative change in healthy life.
modified citrus pectin ("MCP") is also known as small molecule citrus pectin is the product of natural citrus pectin hydrolytic, hydrolysed molecular weight between 2000 and 50000, esterification of 2% to 30%. The role of hydrolysing is to cut off the direct chain of pectin to reduce the molecular weight, and the second is to reduce esterification. MCP is easily absorbed by the intestines and enters the bloodstream, directly stimulating the immune system throughout the body, which can also bind to heavy metals in the blood and cause it to be excreted. MCP can produce special tumor suppression function because it is rich in semi-lactose monos. MCP can significantly improve appetite, help increase immune function and regulate immune disorders, reduce cholesterol to prevent atherosclerosis, reduce blood lipids, blood sugar, treat and prevent obese fatty liver, treat a variety of cancers, has a good anti-alcohol effect. As a result, MCP can be used to prepare immune-enhancing medicines, foods and health products.
common pectin due to large molecular weight, high esterification, low solubility in water, low utilization rate in the body. It is used to relieve the absorption effect of alcohol and weak effect on the breakdown of alcohol entering the body, and is far less effective in alleviating headache and nausea symptoms after drinking than low ester pectin. Low-ester pectin uses bioenzyme technology to control the molecular weight and esterification of pectin within a certain range, so that the water solubility of pectin is better, not only in the gastrointestinal formation membrane to prevent the absorption of alcohol to protect the gastrointestinal tract, but also into the blood to promote alcohol decomposition into carbon dioxide and water.Figure 1 the wake-up rate of different products
pectin and common de-icing products compared to the effect
pectin is derived from the plant community soluble dietary fiber, is a kind of acidic polysaccharide rich in semi-lactose aldehyde acid, is the structural component of the plant cell wall, by the FAO/WHO
Food Additives
Joint Committee recommended as
Food Additives
. In milk, jelly, beverages, ice cream and other foods can be used as thickeners, gels and stabilizers are widely used. Therefore, pectin as a food raw materials safe and reliable, can be long-term consumption.
From pumpkin, sweet potato, sunflower plate, tofu wood, tomatoes, dragon peel, watermelon skin, etc. of low-ester pectin have detox and anti-drunk activity, from apple peel, citrus peel, lemon peel, grapefruit skin and other polymer high-ester pectin through bioenzyme technology transformation and low-ester molecular weight pectin has better anti-drunk activity.Figure 2 anti-drunk effect of different products figure
According to animal experiments, pectin has a better anti-drunk effect, low-ester pectin and the market anti-alcohol products, anti-drunk effect and similar products, wake-up effect and similar products on the market compared to the effect is better. Figure 1 and Figure 2 are a comparison of pectin and similar products on the market to de-alcohol and anti-drunk effects.
1 shows a 52-degree red star two-pot head-made mouse drunken model after feeding different products 2 childhood wake-up rate. In terms of wake-up effects, product pectin is much higher than other product groups. Figure 2 shows mice fed different products, using a 52-degree red star two pot head to create a drunk model at 30min intoxication rate. Anti-drunk effect, the product pectin and similar products on the market equivalent.
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