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    Home > Biochemistry News > Biotechnology News > The effect of vitamin C and heat therapy in combination with treatment of refractory lung cancer is significant.

    The effect of vitamin C and heat therapy in combination with treatment of refractory lung cancer is significant.

    • Last Update: 2020-06-08
    • Source: Internet
    • Author: User
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    For patients with advanced non-small cell lung cancer, the surgical opportunity has been lost due to late staging, and the side effects associated with chemotherapy and molecular targeting often prevent this part of the patient from advanced lung cancer from completing the entire treatment processIs there any way to prolong a patient's life at this point?the results of the research from DrJunwen's team at the Cancer Center of The Prayer Hospital of Guangzhou University of Traditional Chinese Medicine, a solution was given that high-dose vitamin C (vitC) combined ionic radio frequency deep heat therapy (mEHT) could prolong the survival of patients with advanced non-small cell lung cancer and significantly improve their quality of lifeon the basis of pre-research, DrJunwen District's team conducted Phase II randomized controlled clinical trials, including 97 patients in Phase IIIB-IV NSCLC, and patients in the trial group received 3 times a week, a total of 25 vitC and mEHT joint support therapy, and the control group received only supportive treatment, comparing the tumor size, quality of life, non-progression (PFS) and total survival (OS) of the two groupsAccording to the latest cut-off data data on May 1, 2019, after 10 months of median follow-up, vitC combined mEHT significantly improved the quality of life and improved PFS and OS compared to the control groupStudy Results: Treatment Group vs Control Group:1There was no significant difference in the scores of the pre-trial quality-of-life assessment scale, and the treatment group showed significant improvement in physical function and mood after 9 weeks of treatment;2Over time, there was a significant decrease in fatigue, nausea and vomiting, pain, difficulty breathing, loss of appetite and constipation in the treatment group; 3PFS: 3.0 months vs 1.85 months;4OS: 10 months vs 7.5 monthssuggest that patients with advanced NSCLC can benefit from vitC combined mEHT therapy, extending PFS and OS also found that an interesting phenomenon was observed from the level of fasting vitC in lung cancer patients, and that the later the stage of the disease, the lower the level of fasting vitC, the positive correlation between the two The results of pharmacokinetics suggest that patients with pathology of squamous cell carcinoma are more sensitive to vitC combined mEHT therapy the principle of treatment
    this study is the first domestic and foreign large-dose vitC and radiofrequency deep heat therapy for use in patients with advanced lung cancer Foreign studies have confirmed a significant increase in the content of redox active iron in tumor tissue, when the use of high-dose vitC infusion, the body vitC reached pharmacological concentration, with the active iron molecules to react, produce hydrogen peroxide and free radicals, hydrogen peroxide in the extracellular fluid will selectively destroy the DNA of cancer cells, leading to their death The principle of RF deep heat therapy is to use radiofrequency electromagnetic field to act on deep tissue, to use thermal effect selective destruction, anti-killer disease cells to achieve therapeutic purposes, characterized by the nano-range energy release, the energy utilization efficiency of which can be increased by 3-4 times The study found that the combination of high-dose vitC and RF deep heat therapy can significantly increase the peak concentration of vitC in the body, indirectly suggesting that the combination of the two play a two-pronged, synergistic anti-tumor effect at present, lung squamous cell carcinoma accounts for about 30% of non-small cell lung cancer, is a recognized incurable disease, in terms of treatment options are relatively limited The results of this study are undoubtedly a boon for patients with squamous cancer, and once the mechanism of action is identified, it will be a promising treatment option vitC combined mEHT can significantly reduce patient fatigue, enhance appetite, reduce local pain and other discomfort, improve the quality of life, extend life, the researchers suggest that it as one of the conventional methods of tumor support treatment, and even advance to the early stage and progression of cancer, to help prevent secondary tumors, improve the quality of life, extend survival, so that patients get better efficacy anti-tumor treatment finally it is worth noting that all viC anti-cancer mechanism is under the pharmacological concentration of research, and our usual oral vitamin C is physiological concentration, only play the role of supplementary nutrition, oral vitamin C can not reach pharmacological concentration RF deep heat therapy and sauna, Ai bar and other ways are also very different, deep heat therapy can penetrate less than 15cm deep tissue, the epidermis has no sense of heat, the gathering energy is higher, so that it gathers in the tumor tissue to play a role Therefore, do not believe that the folk "iron burning cancer" and so on do not rely on the bias side reference source: A phase I-II clinical trial to evaluate the safety, pharmacokinetics and efficacy of high dose ascorbic acid ynysdd yn fod yn patients with stage III-Non-Cell Small Cancer.
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