544px; text-align: center; background-color: rgb(255, 255, 255);">Tibet sheep and its ecological environment courtesy of Li Xin
544px; text-align: center; background-color: rgb(255, 255, 255);">Tibet sheep and its ecological environment photo544px; text-align: center; background-color: rgb(255, 255, 255);"> courtesy of 544px; text-align: center; background-color: rgb(255, 255, 255);">Li Xin544px; text-align: center; background-color: rgb(255, 255, 255);"> Tibet sheep and its ecological environment 544px; text-align: center; background-color: rgb(255, 255, 255);">photo544px; text-align: center; background-color: rgb(255, 255, 255);"> courtesy of Li Xin As one of the earliest domesticated animals of mankind, sheep play an important role in animal husbandry.
Recently, NCBI Assembly launched the first chromosome-level reference genome of Tibetan sheep.
Li Menghua team completed.
Tibetan sheep adapted to extreme environments Tibetan sheep are mainly distributed in high-cold areas such as the Qinghai-Tibet Plateau.
"Specifically, Tibetan sheep are divided into three ecological types: grassland type, valley type and Euler type.
Li Menghua introduced to "China Science Daily".
Paying attention to and studying Tibetan sheep is not only of important scientific significance, but also of important social, economic and ecological significance.
In 2016, the team’s Yang Ji and other researchers conducted a genome-wide comparison of local sheep breeds under different extreme environments (high altitudes and desert droughts) and found that in order to quickly adapt to extreme environments, sheep produced a series of candidates related to energy metabolism.
In 2019, Hu Xiaoju, who was a Ph.
In addition, the whole genome level test results showed that the genetic composition of argali has infiltrated into Tibetan sheep, covering 5.
HBB 2 2 Good assembly integrity and high accuracy
Good assembly integrity and high accuracy The Contig N50 of the Tibetan sheep genome released this time reached 74.
Researchers conducted BUSCO, sequence identity, and GC-Depth assessments of the genome assembly results, confirming that the genome assembly is complete (95.
The researchers used Hi-C data to further elevate the genome from Scaffold level to chromosome level.
Tibetan sheep live for a long time in the plateau areas of Northwest my country, and are tolerant to hypoxia and high cold.
In addition, the successful assembly of the Tibetan sheep genome is also of great significance for the establishment of a Chinese local sheep germplasm resource bank and biological information database, and the further implementation of germplasm resource protection and germplasm innovation.
Related paper information: org/10.
1093/molbev/msw129" target="_blank">https://doi.
org/10.
1093/molbev/msw129
org/10.
1093/molbev/msw129" target="_blank">https://doi.
org/10.
1093/molbev/msw129 org/10.
1093/molbev/msy208" target="_blank">https://doi.
org/10.
1093/molbev/msy208
org/10.
1093/molbev/msy208" target="_blank">https://doi.
org/10.
1093/molbev/msy208
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