The first wild soybean high-quality reference genome was parsed

Recently, the team of Professor Lin Hanming of Chinese University of Hong Kong and a number of domestic and foreign institutions such as Huada Gene have completed the world's first high-quality reference genome analysis of wild soybeans, which provides an important tool for excavating wild soybean genetic resources and improving and optimizing cultivated soybean varieties. The results of the study were published online in Nature-Newsletter.
is an important basis for current crop improvement programs. In the past, soybean genome research relied mainly on the reference genome of soybean Williams 82, which was cultivated by American scientists, and failed to delve into the unique genetic information of wild soybeans. Although there are reports of genome sequencing of wild soybeans, the assembled genome consists of a large number of fragment segments with low readable gene sequence continuity and no high-quality, reference genomes for wild soybeans.
" soybean genome contains a lot of duplicate areas, and it's difficult to assemble, so we've integrated a lot of data from several of the latest sequencing methods to finally solve the problem. Lin Hanming told China Science Daily.
His team pioneered the sequencing of 31 wild soybeans and cultivated soybeans in 2010, explaining the importance of biodiversity and genomic research in wild soybeans to understanding soybeans, and then successfully using gene sequencing methods for the first time in 2014 to obtain the salt-resistant gene for wild soybeans and successfully apply new soybean resistance varieties, providing a new strategy for improving soybeans. In the study, the team assembled a chromosomal-level reference genome using data from three generations of PacBio sequencing technology, Bionano Genomics bienzyme-cut optical mapping (OM) and high-volume chromosomal composition capture technology (Hi-C).
" wild soybean genome combination in comparative genome and evolutionary research can help to find important genes, and ultimately to improve the cultivation of soybeans, to help develop high-yield, high-quality, reversible soybeans. It is hoped that our research will provide a good reference value for other research teams to excavate the important genetic information of soybeans. Lin said. (Source: Science Network, Gushuang Luxuan)
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