The flu pneumonia vaccine reduces the risk of Alzheimer's disease.

Read: Flu and pneumonia vaccines can reduce the risk of Alzheimer's diseaseCHICAGO, July !---- 28, 2020 - Getting the flu and pneumonia vaccine may reduce the risk of Alzheimer's disease, according to a new study published at the Alzheimer's Association's International Conference (AAIC ® 2020)Three studies published at the conference suggested that getting the flu vaccine at least once reduced the risk of Alzheimer's disease by 17 percentIncrease the number of vaccinations and reduce the prevalence by a further 13%The risk of developing Alzheimer's disease is reduced by up to 40 percent between the ages of 65 and 75, depending on the individual's genesPeople with dementia are at a higher risk of dying after infection (six times) than those who do not have dementia (three times)"After the outbreak of new coronary pneumonia, vaccines have become the focus of public health discussions," said Maria CCarrillo, chief scientific officer of the Alzheimer's AssociationThe key is to understand the benefits of vaccines, which not only protect against viral or bacterial infections, but also protect people's health in the long termCarrillo added: "It's as simple as you're vaccinating against disease, and of course there are other ways to protect your health." Together, these can reduce the risk of Alzheimer's disease and other types of dementiaThe study is still at an early stage and requires large-scale, diverse clinical trials to confirm whether vaccination, as a public health strategy, reduces the risk of developing dementia as he ages"The seasonal flu vaccine may reduce the prevalence of Alzheimer's disease, and previous studies have shown that vaccination may be a way to prevent cognitive decline, but there is no large-scale comprehensive study of the risk of influenza vaccines and Alzheimer's disease." To fill that gap, Albert Amran, a medical student at the McGovern School of Medicine at the University of Texas Health Science Center in Houston, led a team that studied the vast data set of U.Shealth filesAmran and his team found that one flu vaccine reduced the prevalence of Alzheimer's disease (ratio of 0.83, p-lt;0.0001)In patients who received the flu vaccine multiple times, the prevalence of Alzheimer's disease was lower (ratio was 0.87, p-0.0342)As a result, people who keep getting the flu vaccine each year have a lower risk of developing Alzheimer's diseaseThis means that people aged 75 to 84 have a nearly 6 percent lower risk of developing Alzheimer's disease, according to 16 years of data from the health fileThe researchers also found that the earlier the first dose of influenza vaccine, the lower the risk of Alzheimer's disease later in life, meaning that people who first get the flu vaccine at age 60 have a lower risk than those who first get it at age 70"We found in our study that regular, convenient and relatively inexpensive interventions, such as the flu vaccine, can significantly reduce the risk of Alzheimer's disease," Amlan saidWe also need more research to identify the biological mechanisms of this effect, namely why and how the flu vaccine works in the human body, which is important for us to explore effective ways to prevent Alzheimer's disease"The risk of developing Alzheimer's disease in later life may be an effective way to prevent Alzheimer's disease by immunising the pneumonia vaccineDrSvetlana Ukraintseva, an associate professor of research at the Institute of Aging BiodemographicS (BARU) at Duke University's Institute of Social Sciences, and his team studied 5,146 people over the age of 65 who participated in the Cardiovascular Health Study to explore the relationship between pneumococcal vaccination (both vaccinated or unvaccinated seasonal influenza) and the risk of Alzheimer's diseaseThey also included a known genetic risk factor for Alzheimer's disease, the rs2075650G allele on the TOMM40 geneAfter adjusting for sex, race, birth lineage, education, smoking, and number of G alleles, the researchers found that the risk of Alzheimer's disease was reduced by 25 to 30 percent between the ages of 65 and 75 when the vaccine was given to pneumococcal diseasePeople who did not carry the above-mentioned risk genes had the greatest reduction in their risk of developing Alzheimer's disease after being vaccinated against pneumonia, up to 40 percentThe overall number of pneumonia and flu vaccinations in this age group was also associated with a reduced risk of Alzheimer's diseaseHowever, the effect of only getting the flu vaccine is not obvious for the prevention of Alzheimer's disease"Getting the pneumonia vaccine before age 75 can reduce the risk of Alzheimer's disease in later life, depending on the genotype of the individual," Uklarntseva saidThese data suggest that pneumococcal vaccines can be an effective way to personalize the prevention of Alzheimer's disease, especially in people who do not carry specific risk genes"Infections can significantly increase the mortality rate of people with dementia and people with dementia often develop other health conditions, such as viruses and bacterial infectionsThe medical community has begun to investigate whether infections are becoming more serious, more life-threatening, or may cause dementiaJanet Janbek is a PhD student at the University of Copenhagen in Denmark and is also employed by the Danish Dementia Research Centre at Rigshospitalet Hospital Her team used data collected by the National Health Registry to investigate the mortality rates of Danish residents over 65 who went to hospital for infection It was found that people with dementia and hospital visits for infection were 6.5 times more likely to die than those without either condition Among those who participated in the study, those who had dementia alone, or who went to the doctor only for infection, had a three-fold higher mortality rate The highest mortality rate was in the first 30 days after a visit to the hospital The researchers also found that the mortality rate of people with dementia was high for 10 years after the first time they went to the hospital for an infection The mortality rate of all infected patients, including major infections such as sepsis and mild ear infections, was higher than in people who did not have dementia or go to hospital for infection "Our study suggests that these relationships need to be further clarified to identify the causes of higher mortality in people with dementia, particularly the risk factors and biological mechanisms involved," Says Jambeck This will help us to better understand the role of infection in dementia Mr Jambeck added: "From our study, it is also found that the health care system and relatives of people with dementia should pay attention to the situation of people with dementia who are infected so that they can receive immediate treatment." People with dementia also need specialized treatment, even if not for dementia, but for seemingly unrelated infections "。