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    Home > Active Ingredient News > Active Ingredient Products News > The Instruction of Ethanesulfonic acid, 2-[[2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-, sodium salt (1:1)

    The Instruction of Ethanesulfonic acid, 2-[[2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-, sodium salt (1:1)

    • Last Update: 2023-05-13
    • Source: Internet
    • Author: User
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    Ethanesulfonic acid, 2-[[2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-, sodium salt (1:1), also known as Roxadustat, is a new oral medication used in the treatment of anemia in patients with chronic kidney disease.
    The chemical structure of Roxadustat is composed of a unique molecule that has been specifically designed to stimulate the production of erythropoietin, a hormone responsible for the production of red blood cells in the bone marrow.


    Roxadustat has been developed using a novel approach that involves inhibiting the activity of an enzyme calledAMP deaminase, which is responsible for breaking down the important molecule guanosine.
    By inhibiting AMP deaminase, Roxadustat is able to increase the levels of guanosine in the body, which in turn leads to an increase in the production of erythropoietin.
    This increased erythropoietin then stimulates the production of red blood cells, leading to an improvement in anemia in patients with chronic kidney disease.


    Roxadustat has been extensively studied in clinical trials, and has been shown to be effective in improving anemia in patients with chronic kidney disease.
    In addition, Roxadustat has been shown to have a good safety profile, with few side effects observed in clinical trials.


    The use of Roxadustat in the treatment of anemia in patients with chronic kidney disease represents an important advancement in the field of nephrology.
    Chronic kidney disease is a serious condition that affects millions of people worldwide, and anemia is a common complication of this disease.
    Anemia can lead to fatigue, weakness, and other serious health problems, and is often difficult to treat effectively.


    The development of Roxadustat is also significant because it represents a new approach to the treatment of anemia.
    Rather than simply transfusing patients with red blood cells, as is typically done, Roxadustat works at the root of the problem, stimulating the production of red blood cells in the bone marrow.
    This new approach offers the potential for improved outcomes for patients with chronic kidney disease.


    The use of Roxadustat is also important in light of the growing awareness of the need for more gentle treatments that have fewer side effects.
    Roxadustat has been shown to be safe and effective in clinical trials, and represents a promising new treatment option for patients with chronic kidney disease.


    Roxadustat is synthesized through a multi-step process that involves the synthesis of several key intermediates.
    These intermediates are then combined through a series of chemical reactions to form the final compound.
    The synthesis of Roxadustat requires a high degree of technical expertise and is carried out in a controlled environment to ensure the purity and safety of the final product.


    Roxadustat is formulated as a solid oral dose that is taken once daily.
    The dosage of Roxadustat is tailored to the individual patient, based on factors such as the severity of their anemia and their underlying kidney disease.
    The oral dosing form of Roxadustat is convenient for patients and allows for easy administration at home.


    Roxadustat is currently undergoing review by regulatory authorities around the world, with the aim of obtaining approval for its use in patients with chronic kidney disease.
    The development of Roxadustat represents an important advancement in the treatment of anemia in patients with chronic kidney disease, and holds great promise for the future of nephrology.


    In conclusion, Roxadustat is a new medication that is used in the treatment of anemia in patients with chronic kidney disease.
    It works


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