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    Home > Biochemistry News > Biotechnology News > The "Lancet" COVID-19 mRNA vaccine is only 47% effective after 5 months?

    The "Lancet" COVID-19 mRNA vaccine is only 47% effective after 5 months?

    • Last Update: 2021-10-21
    • Source: Internet
    • Author: User
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    More than 3.
    4 million subjects confirmed that the protective effect of the mRNA COVID-19 vaccine after 5 months is only 47%

    What is the protective effect of Pfizer mRNA vaccine against COVID-19?

    The Ministry of Public Health of the United Kingdom and the Ministry of Health of Israel respectively released real data on the prevention of Delta mutant strains in their own vaccines, but the two results are surprisingly different
    .

    Infection prevention rate: 88% VS 39%

    On July 23, 2021, the National Broadcasting Corporation Financial Channel (CNBC) reported the latest report of the Israeli Ministry of Health, which is extremely worrying
    .


    The Israeli report shows that the Pfizer/BioNTech mRNA vaccine has a protection rate of only 39% against symptomatic COVID-19 caused by the Israeli Delta mutant strain


    It is reported that Israel has begun to vaccinate its citizens for the third time
    .

    At the same time, on July 21, 2021, the New England Journal of Medicine (NEJM) published the public health department's vaccine protection data against the real world of Delta.
    This is the first published real-world effectiveness of the Delta mutant strain.
    Research data
    .


    After full vaccination with Pfizer mRNA vaccine, the protection rate against symptomatic COVID-19 caused by the Delta mutant strain was 88%


    Both of these values ​​are correct.
    After in-depth analysis of the data behind them, we found that:

    The reduced protective effect of the vaccine occurs in the following two situations:

    1) Extend the vaccination time;

    2) The elderly
    .

     

    In the data of the United Kingdom and Israel, the time of vaccination is completely different, and the proportion of elderly people is also very different, so the results obtained are naturally different
    .

     

    But two questions have been floating in our minds, lingering ——

    1.
    Does the Delta mutant strain reduce the protective effect of the vaccine? 2.
    Will the vaccine protect us after half a year of vaccination?

     

    On October 4, 2021, an American scholar's study of more than 3.
    4 million people was published in The Lancet
    .


    The results show that:

    1) After vaccination with Pfizer, the infection protection rate decreased from 88% to 47% at the 5th month; 2) The reduced protection of the vaccine against infection is due to the decrease in immune antibodies over time, not the Delta mutation Strains of evasion vaccine; 3) After being fully vaccinated with Pfizer, the 5-month hospitalization/death protection rate for COVID-19 remains at 88%!

     

     

     

    We look at the defensive population in this study:

    From December 14, 2020 to August 8, 2021, the electronic health record of Kaiser Permanente Southern California, a health care institution in California, USA
    .

    A total of 343,957 subjects were included, of which 52.
    4% were women
    .


    All were 12 years old and above, with a median age of 45 years


     

     

    The anti-epidemic weapon for this group of people is the BNT162b2 mRNA vaccine from Pfizer Biotech
    .

    The vaccine is also one of the three most protective vaccines developed by humans
    .

    The offensive situation of the new coronavirus mutant: The new coronavirus continues to mutate and alternately attack humans until the most infectious mutant of the new coronavirus, the Delta mutant strain, is screened out
    .


    This is also one of the three most infectious viruses in human history


    Delta mutant strains began to appear in California in April, but only accounted for 0.
    6%; but in June, Delta mutant strains began to account for more than half, and Delta mutant strains became the absolute mainstream strain (86.
    5%) in July
    .

     

     

    Prevent infection (within 1 month)

    Within one month after the completion of vaccination, the protection against COVID-19 is 88%, of which the protection against COVID-19 is 80%
    .

    Among them, the protection rate against Delta mutant strain infection was 93%
    .

    At this stage, humans rely on powerful vaccines to defeat COVID-19, and the number of new coronary pneumonia cases has fallen sharply
    .


    Israel has become the benchmark for all countries in the world in terms of vaccine coverage


     


    The vaccine's protection against COVID-19 continues to decline

     

     

    Prevent infection (within 5 months)

    Five months after the completion of vaccination, the protection rate of the vaccine against COVID-19 had dropped to 47%, and the protection rate for people 65 years of age and older was 43%
    .

    Among them, the protection rate against Delta mutant strain infection was 53% (4 months)
    .

    In view of the fact that this stage is catching up with the emergence of the Delta mutant, the director of the US Centers for Disease Control and Prevention burst into tears on the spot, expressing despair and panic that "the battle has changed
    .


    " Subsequently, the United States followed the example of Israel and began to strengthen vaccination


    Within one month of completing the vaccination, the vaccine has a protection rate of 87% against severe COVID-19, of which the protection rate against Delta mutant infection is 93%
    .

     


    Vaccine protection against serious illness/death remains unchanged

     

     When fully vaccinated for 5 months, the protection rate of the vaccine against severe COVID-19 was 88%, almost no reduction
    .

    American medical scientists believe that since humans cannot prevent infection by the Delta mutant strain, they need to abandon the practice of relying on universal vaccination to prevent infection; instead, they will focus on preventing serious illness/death, but the current vaccine is sufficient to complete this prevention
    .


    Of course, the task is still grim, so we need to pay attention to and protect the vulnerable and susceptible people


    Therefore, the U.


    S.
    Food and Drug Administration (FDA) and the U.
    S.
    Centers for Disease Control and Prevention (CDC) have successively rejected President Biden's plan to vaccinate only people over 65 with immune dysfunction
    .
    It is proposed to strengthen the vaccination of adults with underlying diseases and adults engaged in high-risk jobs
    .

     


    Summarize

    1. Five months after vaccination, the Pfizer vaccine's protection against the new coronavirus is only 47%;

    2. However, the protective ability of Pfizer vaccine against severe illness/death remains unchanged at 88%;

    3. The Delta mutant strain has no immune escape, but it is extremely infectious
      .

     

    Unfortunately, due to the emergence of delta mutants, humans’ hopes of eliminating the new coronavirus through vaccination have almost been dashed.
    They have to accept the "normal life of the new coronavirus", that is, no longer overemphasize the prevention of infection, but the prevention of serious illness/death
    .

    According to data from Los Angeles, USA, after full vaccination, the severity rate of the disease was 3.
    2%, and the case fatality rate was reduced to 0.
    2%; Merck’s newly released oral antiviral drugs can reduce the incidence of severe infections with high-risk infections by 50%, and none in the treatment group Death cases (8 deaths in the placebo group)
    .
    Through the model of vaccination + oral antiviral treatment, it may be possible to expect to return to a new normal life
    .

    But we are more expecting friends to wear masks to stay away from the virus without these drugs
    .
    I hope that there is no disease in the world, and the medicines on the shelves are full of dust
    .

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