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    Home > Biochemistry News > Biotechnology News > The Lancet sub-issue: What happened to those new crown patients who recovered and then "turned yang"?

    The Lancet sub-issue: What happened to those new crown patients who recovered and then "turned yang"?

    • Last Update: 2020-09-17
    • Source: Internet
    • Author: User
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    A joint team of researchers was recently published in The Lancet Diseases, a sub-issue of The Lancet.
    researchers followed 651 patients with neo-crown pneumonia who were discharged from Wuhan Lung Hospital between January 11 and April 1 this year.
    they found that 23 (3%) of those patients who met the discharge criteria and were confirmed negative by two nucleic acid tests were re-yangned during follow-up.
    the reason why these patients' nucleic acid test results are "yin and yang"? Do antibodies in their bodies protect them? Let's take a look at the detailed results given by the researchers.
    the average age of 23 nucleic acid test patients was 56 years (27.0-89.0 years), including 12 women and 11 men.
    the last time these patients were admitted to hospital because of COVID-19, 12 (52%) were moderate, 9 (39%) were serious and 2 (9%) were critically ill.
    time from discharge to nucleic acid testing was 15.0 days (4-38 days).
    patients discharged from the hospital nucleic acid detection and re-yang timeline (sic, asymptomatic patients, pictured: References s1) patients' antibody levels, COVID-19 symptoms and clinical consequences When nucleic acid testing turns yang, patients are also tested for serological testing of new coronavirus antibodies.
    serological test is based on collomic gold immuno-layering test paper test.
    test results showed that IgG and IgM antibodies were positive in 7 (30%) patients, IgG antibodies were positive in 5 (22%) patients, and IgM test results were negative.
    two antibody tests were negative in the remaining 11 (48%) patients.
    In this group, 15 (65%) patients showed no symptoms when retrmped, while 8 (35%) patients showed at least one symptom associated with active COVID-19, specifically six patients with fever, two with cough, one with fatigue, one with breathing difficulties, and one with chest tightness.
    As of the last follow-up on 4 April, all 23 patients were still alive, 18 (78 per cent) had recovered and were discharged again, 4 were still hospitalized for medical care and one was self-isolated at home.
    discussions, the researchers said in comments that the reasons for the re-yanging of nucleic acid testing in recovering patients have not been fully clarified.
    Although nucleic acid positive results in asymptomatic rehabilitation patients may be associated with residual non-pathogenic viral substances, positive results in patients showing symptoms mean that the disease may return.
    given that 52 percent of patients in this group carry antiviral IgG antibodies and 30 percent carry IgM antibodies, this means that their immune systems produce partial immune recognition of the new coronavirus.
    the effectiveness of antiviral antibodies in removing COVID-19 remains an issue that needs to be answered because 35% of patients develop one or more COVID-19-related symptoms.
    whether patients can continue to spread the virus after discharge from the hospital deserves further research.
    to prevent a second wave of COVID-19 infection, the researchers recommend that patients recovering from COVID-19 be clinically observed for at least 14 days after discharge.
    : (2020) Assessment of patients who tested positive for COVID-19 after recovery. The Lancet Infectious Diseases.
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