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Editor in charge: Food Science
Original title: National Edible Fungus Processing Technology Research and Development Center Medicine and Food Dual-use Resource Platform has made progress in the study of spectrum-effect relationship, component knockout and molecular docking technology for rapid identification of active ingredients and mechanism of action
The result was published in the "Food and Chemical Toxicology" magazine with the title "A rapid method and mechanism to identify the active compounds in Malus micromalus Makino fruit with spectrum-effect relationship, components knock-out and molecular docking technology" (Instant IF: 5.
The fruit of Malus micromalus Makino, a genus of Rosaceae, has a rich variety of chemical components, including flavonoids, organic acids and volatile components.
In this study, the influence of the fruit of Begonia xifuensis on tyrosinase activity was combined with the HPLC fingerprint to construct a "spectrum-effect model", the active substances were screened out through the spectrum-effect relationship, and the component knockout method and UPLC-MS/MS method Structure identification of target components.
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