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When it comes to the medicinal and therapeutic properties of marijuana, an unsolved mystery is whether there is an "accompanying effect", that is, the plant as a whole has greater analgesic effects than any of its individual parts
"Many people take marijuana and cannabinoids for pain relief," said lead researcher Dr.
Terpenes are aromatic compounds found in many plants and are the basic components of essential oils
Researchers found that when used alone cannabinoid terpenes themselves can mimic the effects of cannabinoids, including reducing pain
"In a way, this was unexpected," Streicher said
Dr.
When cannabinoids (such as THC) enter the body, it binds to one of two cannabinoid receptors, including the most abundant CB1R or CB2R
Behavioral studies in mouse models show that when four terpenes are administered alone, all four terpenes reduce pain sensitivity and at least reduce three of the four typical side effects of cannabinoids: less pain and lower body temperature , Reduced exercise and paralysis, which is a freezing behavior related to the psychoactive of cannabinoids
Dr.
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