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    Home > Active Ingredient News > Study of Nervous System > The long-term loneliness of middle-aged people exacerbates the risk of dementia. Short-term loneliness helps prevent dementia...

    The long-term loneliness of middle-aged people exacerbates the risk of dementia. Short-term loneliness helps prevent dementia...

    • Last Update: 2021-04-19
    • Source: Internet
    • Author: User
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    Loneliness is an experience, or rather, a state.

    Some people are afraid of this state, while others enjoy it.

    People who are afraid of loneliness usually feel lonely because their social needs are not met.

    Loneliness is a negative emotion, which reflects the imbalance between ideal social relations and actual social relations.

    Obviously, these two relationships are balanced for people who enjoy loneliness.
    Although they are lonely but not lonely, there is no sense of loneliness.

    However, people who feel lonely, especially middle-aged people, have to find a way to balance these two relationships, because long-term loneliness will affect physical and mental health.

    Previous studies have found that people who are lonely are more likely to develop type 2 diabetes.

    Not only that, loneliness is also related to the risk of Alzheimer's disease.

    Recently, in a new study published in the Journal of the Alzheimer's Association "Alzheimer's & Dementia: The Journal of the Alzheimer's Association", a research team led by Professor Qiu Weiqiao from Boston University School of Medicine showed that middle-aged people continue to Loneliness can threaten brain health and increase the risk of dementia in the future.

    However, compared with people who have never felt lonely, those who have experienced short-term loneliness have a lower risk of developing dementia.

    It seems that occasionally feeling lonely is not a bad thing.

    We should face it normally and step out actively.

    Loneliness is a subjective experience.
    Although it does not have the status of a clinical disease, it is indeed related to a series of negative health consequences, including sleep disorders, depressive symptoms, cognitive impairment, type 2 diabetes and stroke.

    Everyone will experience loneliness more or less in their life.

    However, different people experience different lengths or degrees of loneliness.

    Therefore, people who get out of loneliness (transient loneliness) should have different health consequences from those who experience loneliness for a long time (persistent loneliness).

    In order to clarify the relationship between transient loneliness or persistent loneliness and dementia or Alzheimer’s disease, the researchers examined 2880 patients with normal cognition from the Framingham (Framingham) heart study.
    Annual data.

    They define loneliness as no loneliness, transient loneliness, occasional loneliness, and persistent loneliness.

    Researchers analyzed whether persistent loneliness is more predictive of Alzheimer’s progression in the future than transient loneliness, and identified genetic risk factors for Alzheimer’s disease, such as apolipoprotein ε4 (APOE ε4) alleles gene.

    Previously, a research team led by Professor Jia Jianping from Xuanwu Hospital of Capital Medical University conducted an analysis for the carrying situation of APOE ε4 in Chinese for the first time, and finally confirmed the strong association between APOE ε4 and Alzheimer's disease.

    The results of the analysis showed that persistent loneliness was associated with a higher risk of Alzheimer's disease; compared with people without loneliness, transient loneliness was associated with a lower risk of Alzheimer's disease after 18 years.

    This result is still valid after considering the influence of factors such as age, gender, education level, social relationships, living alone, physical health, and genetic risks.

    The corresponding author of the study, Professor Qiu Weiqiao of psychiatry, pharmacology and experimental therapeutics, explained: “Persistent loneliness is a threat to brain health, and mental recovery after bad life experiences may explain why short-term loneliness can prevent Alzheimer’s.
    The role of Zheimer’s disease.

    "Researchers believe that these results will prompt further research into the factors that enable individuals to recover from adverse life events.

    Health professionals should carry out appropriate interventions on individuals, which will help avoid persistent loneliness and promote current and future brain health to effectively prevent Alzheimer’s disease.

    Link to the paper: https://doi.
    org/10.
    1002/alz.
    12327 https://doi.
    org/10.
    1002/alz.
    12153 Related research: Neurobiological research: "loneliness" is the opposite of "wisdom", the smarter the less Feeling lonely What happens in the brain when you feel lonely? The results are surprising.
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