The measurement of oxygen permeability of medical plastic bottle packaging

Key words: medical plastic bottle, oxygen resistance, oxygen permeability Medical plastic bottle, with its advantages of light weight, high strength, good sealing and pressure resistance, is gradually replacing medical glass bottle, and is widely used in the packaging field of oral solid medicine and liquid medicine Oxygen is an important factor affecting the quality and safety of drugs In order to prevent the influence of oxygen on drugs, the plastic bottles for medicine should have good oxygen resistance performance to ensure the quality and safety of products In this paper, combined with the perme Bomi ox2 / 230 oxygen transmittance test system of Labthink blue light, the detection method of oxygen transmittance of medical plastic bottle packaging is introduced Oxygen permeability mainly refers to the barrier effect of medical plastic bottles on oxygen The performance of oxygen resistance directly affects the product quality during the shelf life of drugs, and is also an important factor in the analysis of shelf life This test can solve the problem of oxidative deterioration of drugs caused by oxygen sensitivity Labthink Languang ox2 / 230 oxygen transmittance test system adopts the test principle of constant pressure method (i.e Coulomb electricity method) The equipment is equipped with constant temperature and humidity control function The whole test process is controlled by computer and tested automatically The user only needs to install the sample, click the test to fully automatic test At the end of the test, the user can automatically judge and issue the test report The general test process is as follows: Place the pre-treatment medical plastic bottle sample in the test chamber, oxygen flows outside the plastic bottle, and high-purity nitrogen flows inside the plastic bottle Due to the existence of oxygen concentration gradient, oxygen molecules diffuse from the outside of the plastic bottle to the high-purity nitrogen inside through the film, and are carried to the sensor by the flowing nitrogen, through which the oxygen concentration measured by the sensor is analyzed So as to evaluate the oxygen resistance of the sample The test schematic diagram is as follows: of course, after ensuring that the oxygen resistance index of pharmaceutical plastic bottle packaging is qualified, other indexes such as moisture resistance and sealing need to be controlled to ensure the quality of products within the shelf life For more information about related testing instruments, you can visit www.labthink.cn for specific information Jinan Languang Electromechanical Technology Co., Ltd is willing to enhance exchanges and cooperation with enterprises and institutions in the industry Of course, after ensuring that the water vapor transmission index of pharmaceutical plastic bottle packaging is qualified, other indexes such as moisture resistance and sealing need to be controlled to ensure the quality of products within the shelf life For more information about related testing instruments, you can visit www.labthink.cn for specific information Jinan Languang Electromechanical Technology Co., Ltd is willing to enhance exchanges and cooperation with enterprises and institutions in the industry.