echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > The micro-human brain implanted in the mouse developed capillaries.

    The micro-human brain implanted in the mouse developed capillaries.

    • Last Update: 2020-08-10
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    For the first time, researchers have developed tiny human brains that grow blood vessels in the lab, the Daily Mail of London reported.
    two weeks after implanting tiny human brains that were only one millimeter long into the brains of mice, the researchers found that the micro-human brain grew capillaries and penetrated through the center, thus providing a blood supply.
    the results are expected to help researchers develop larger brains to better study how the brain works.
    future, researchers hope to use this artificial brain tissue to treat stroke patients.
    a team of scientists at the University of California, Davis, who was first inspired by ben Waldeu, an vascular neurosurgeon at the university who has worked on the rare disease of smoke disease.
    blockage in areas such as the end of the two-sided inner neck artery, preventing blood from reaching other parts of the brain.
    scientists often use laboratory-grown stem cells to study the brain.
    but these stem cells still play a very limited role in understanding complex structures and organs.
    Of all human organs, the last thing humans know is the brain, and the micro-brains used for experiments give researchers an unprecedented opportunity to explore how different areas of the brain work together. "The whole idea of this micro-brain is that one day we can use the patient's cells to develop the structure of the brain he has lost," says Dr. waldo,
    .
    "We found brain damage through a CT scan, but there was nothing we could do."
    even after surgery and physiotherapy, many of them suffer permanent nerve damage such as paralysis.
    "We sometimes move the patient's artery to the top of the brain and let the blood vessels grow into the brain," Waldo said.
    when the process is reproduced with the help of a micro-brain, we found that blood vessels can group themselves.
    "micro-brain developmental regions expand rapidly, from immature stem cell populations to more complex structures.
    as the micro-brain develops, the blood flow pathway also reproduces a disorder: when the size becomes too large at some stage, the middle of the microbrain begins to die.
    to overcome this, Waldo and his colleagues combined stem cells with other human cells to promote blood vessel formation.
    team used endothelial and stem cells from the same patient who was undergoing routine surgery to ensure that they did not reject each other.
    when stem cells grow into small clumps of globular, the researchers wrap them together with endothelial cells and incubate them with a special gel.
    after a short period of incubation and growth, the researchers transferred the tiny brain from gel to mouse brain.
    researchers cut a small hole in the mouse's brain and transplanted it in it.
    despite brain surgery, the mouse is still alive and will become a "receptor" for the micro-human brain for the next two weeks.
    two weeks later, blood vessels in the brains of mice successfully penetrated into the micro-human brain.
    the tiny human brain even grows its own capillaries.
    they spread throughout and extend edited all the way to the center.
    based on this finding, future research will be able to expand on larger organ tissues so that researchers can learn more about the more advanced functions of the human brain.
    "It's a great finding," said Christophe Koch, director of the Allen Institute of Brain Science sat in Seattle, "but the research is still early."
    ":"The next problem is to connect these cells to the loops that can receive processing information.
    ", "when I look at the world, I feel that it's space-ordered, with left, right, far, and near space, because my cerebral cortex is organized, reflecting the regularity of the world."
    but such organs as micro-brains do not yet have such tissues.
    " article on the study was published in the journal NeuroReports.
    Source: NetEase Technology.
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.