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    Home > Food News > Food Articles > The molecular mechanism that regulates the energy metabolism of yak skeletal muscle was discovered

    The molecular mechanism that regulates the energy metabolism of yak skeletal muscle was discovered

    • Last Update: 2023-02-03
    • Source: Internet
    • Author: User
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    Recently, the yak resource and breeding innovation team of Lanzhou Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences, discovered key candidate genes, regulators and signaling pathways involved in regulating energy metabolism and muscle fiber type conversion in yak skeletal muscle, which provided an important reference
    for the genetic improvement of yak quality traits.
    The findings were published in Meat Science
    Skeletal muscle in animals is made up of
    several types of muscle fibers.
    Studies have shown that muscle fiber type is closely
    related to meat quality traits such as meat color, pH value, shear force and intramuscular fat content.
    At present, the molecular regulation mechanism of yak muscle fiber type formation and conversion is not clear
    The researchers performed transcriptome sequencing analysis on the biceps femoris and the external oblique muscle dominated by fermented muscle fibers of yak oxidized muscle fibers, and identified a total of 1436 differentially expressed genes, 1172 differentially expressed long-chain non-coding RNA and 218 differentially expressed cyclic RNA, and further analysis found that the target genes regulated by differentially expressed long-chain non-coding RNA and cyclic RNA were mainly involved in the signaling pathways
    related to energy metabolism in skeletal muscle 。 The molecular regulatory network related to skeletal muscle energy metabolism and muscle fiber type conversion was also constructed, which laid a foundation
    for the analysis of the regulatory mechanism of yak meat quality trait formation.
    The research was supported
    by the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences and the National Natural Science Foundation of China.
    (Correspondent: Fu Jinzhong)
    Original link: https://doi.
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