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    Home > Biochemistry News > Biotechnology News > The most comprehensive human genome sequencing to date has been completed with an increase of 200 million base pairs and more than 2,000 genes than the original image

    The most comprehensive human genome sequencing to date has been completed with an increase of 200 million base pairs and more than 2,000 genes than the original image

    • Last Update: 2021-06-04
    • Source: Internet
    • Author: User
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    20 years ago, scientists announced that they had read all the deoxyribonucleic acid (DNA) of a person.


    Humans have tens of thousands of genes, which are stored in DNA molecules.


    Scientists started the human genome sequencing project in 1990 and published the first draft of the human genome in 2001.


    The new version of the genome is drawn by the "telomere to telomere" (T2T) consortium.


    The researchers chose to read DNA from a cell line called CHM13.


    Every piece of DNA in ordinary human cells has two copies.


    To assemble the genome sequence, the research team used two technologies: one is a sequencing technology that can read very long (more than 1 million base pairs) fragments; the other is extremely accurate and can handle very small differences Fragmentation (such as multiple copies of the same gene) technology.


    In July 2020, the team announced the complete sex-determining human X chromosome.


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