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Phenols, such as phenols and paraphenols, are a widely used and highly used chemical that can be used in the preparation of pesticides, pesticides, plastics, dyes, pharmaceuticals, polymers, etc. However, the industrial production of these phenolic compounds is often a process of high energy consumption and high pollution, and there are problems such as excessive oxidation and low yield and many by-products in production. However, these phenolic compounds are now expected to be prepared step-by-step through environmentally friendly benzoylation reactions using clean oxygen sources such as hydrogen peroxide, rather than the cumbersome multiple reaction steps required by traditional methods, high energy consumption, high pollution, and low yield (traditional methods yield only 5%)
China
. This is an important achievement of Wang Jun, Associate Professor Zhou Yu and Professor Yan Ning of the National University of Singapore in the reaction of the zeolite molecular sieve catalytic aromatic hydroxylation preparation of phenolic compounds in Nanjing University of Technology's National Key Laboratory and Chemical Engineering, and the relevant papers were published in Nature Communications recently.
According to Associate Professor Zhou Yu, benzene is an inert substrate, and the product of phenol than substrate benzene more lively, in the past traditional methods of preparing phenol, in the process of producing phenol, will continue to oxidize phenol, resulting in a series of serious side effects (and produce some adverse by-products), and the use of traditional catalyst utilization rate is not high, reaction time is often up to ten to dozens of hours, difficult to meet the needs of industrial catalysis. Professor Wang Jun's team used innovative methods to prepare a zeolite molecular sieve containing three elements of vanadium, silicon and oxygen (regulated holes, large contact area, conducive to efficient and rapid reaction) catalyst, used in the chemical reaction between benzene and hydrogen peroxide, to produce phenol and other phenols (i.e. hydroxyl reaction of benzene).
The application of this new catalyst, so that hydrogen peroxide and benzene reaction to produce phenol, will no longer have adverse side effects with the more lively phenol, produce adverse by-products, but let the hydrogen peroxide "directed" only with benzene reaction, directly one step to prepare phenol, to obtain pure benzene The yield of phenol is very high (phenol yield and hydrogen peroxide utilization rate are as high as 30%, and the time and space yield of 10-5 mol/cc.s is much larger than the industrial Weiss window (10-6 mol/cc.s times more than ten times); And the reaction process only produces water, and no other waste and other pollution emissions, green environmental protection; And this new catalyst, not from penta-price to four-price to produce free-based (and thus produce more side reactions) and trigger a reaction, but in the reaction without price change, through a non-free-based rapid response to produce phenols, thus achieving the instantaneous occurrence of the reaction, the reaction almost instantaneously completed (reaction time <30 s), greatly improving the efficiency of obtaining phenol.
the urgent pressure of energy and environment, the development of green chemical process, in the industrial production process urgently need to use high selectivity, high atomic utilization rate of the new catalytic process, and this development, mainly depends on the development and development of new catalytic materials. This highly active catalyst developed by Wang Jun's research team has a very high efficiency in aromatic hydroxylation reaction and is expected to achieve industrial scale production of phenolic compounds such as phenol, showing important potential industrial application prospects.
The innovative preparation method of this catalyst also has a wide range of universality, can further build a zeolite molecular sieve containing different metals (such as iron, copper, manganese and other elements), to prepare an efficient multi-phase catalyst, promising to achieve other types of chemicals green production process.
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