echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Endocrine System > The new crown is "yang", what is the role of vitamin C?

    The new crown is "yang", what is the role of vitamin C?

    • Last Update: 2023-02-03
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    For medical professionals only



    Evidence-based medicine, rational use of medicine


     

    Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is recommended among the anti-inflammatory drugs in the "New Coronary Pneumonia Diagnosis and Treatment Plan Treatment Drug Information Collection (Second Edition)
    ".
    So after the adjustment of epidemic prevention and control measures, with the menacing of positive patients, what is the role of vitamin C in drug treatment? How to administer medication?



    Pharmacological effects[1]
    participate in amino acid metabolism, neurotransmitter synthesis, collagen and histocellular interstitium synthesis, can reduce capillary permeability, accelerate blood clotting, stimulate coagulation function, Promote iron absorption in the intestine, promote the decline of blood lipids, increase resistance to infection, participate in detoxification function, and have the effect of antihistamine and preventing the production of carcinogens (nitrosamines).


    Reference dosage
    for "new coronary pneumonia" 1.
    Infusion regimen for light and ordinary new coronary pneumonia: 2g added to 5% glucose injection 250mL, intravenous drip, once a day, 7-14 days 1 course of treatment
    .

    2.
    When the disease progresses to mild and ordinary patients and there is a risk of turning into severe disease: 50-100mg per day
    kg-1, intravenous drip
    .

    3.
    “ Prevention and control of cytokine storm": 100-200 mg per day
    kg-1, intravenously
    .
    The goal is a significant improvement in the oxygenation index during the period of continuous use
    .
    For the dosage of off-label medication
    .

    【Source of evidence】1.

    The National Health Commission's "On Printing and Distributing the Management Standards for Light and Common Cases of Novel Coronavirus Pneumonia (Second Edition)" mentions the infusion scheme
    for mild and ordinary new coronary pneumonia.

    2.
    The "Shanghai 2019 Coronavirus Disease Comprehensive Treatment Expert Consensus" mentions that if the disease progresses significantly and there is a risk of turning into severe disease, high-dose vitamin C treatment
    is recommended.
    In addition, the prevention and treatment of "cytokine storm" recommends the use of higher doses of vitamin C
    .

    3.
    Zhongnan Hospital of Wuhan University registered and applied for "a randomized, open, parallel-controlled clinical study evaluating the efficacy and safety of enteric-coated capsules of diammonium glycyrrhizinate combined with vitamin C tablets in the treatment of common novel coronavirus pneumonia (COVID-19) on the basis of clinical standard antiviral therapy".

    Among them, the dosage of vitamin C tablets is 0.
    5g, and the drug is taken once
    a day.

    4.
    UpToDate: Vitamin C as an antioxidant, used in the adjuvant treatment of various acute and chronic infectious diseases, has been widely used in the treatment of sepsis, combined with hydrocortisone can act synergistically on the inflammatory cascade
    .

    Other clinical applications [2-7].




    • Scurvy: used for the treatment of scurvy, can also be used for various acute and chronic infectious diseases and purpura and other auxiliary treatment
      .
      For the prevention and treatment of
      vitamin C deficiency.

    • Keshan disease: high-dose intravenous injection is used for Keshan disease, rescue in cardiogenic shock
      .

    • Chronic iron poisoning: Vitamin C promotes the chelation of iron by deferoxamine, which accelerates iron excretion
      .

    • Idiopathic methemoglobinosis: treatment
      of idiopathic methemoglobinosis.

    • Enhance resistance: enhance the body's resistance, used to prevent and treat various acute and chronic infectious diseases or other diseases
      .

    • Wound healing: used for post-illness recovery period, wound healing period and adjuvant treatment
      of allergic diseases.



    More popular drugs in Corey, where to learn?

    How to properly supplement vitamin C during the epidemic?
    What drugs can vitamin C not be taken with?
    Can vitamin C supplementation lower uric acid?


    The "evidence-based medicine" module you want is the 👇 dry drug decision assistant


    References:

    [1] None.
    Compilation of new coronary pneumonia diagnosis and treatment plan treatment drug information (second edition)[J].
    Zhongnan Pharmacy,2020,18(3):14.
    )

    [2] Drug information: vitamin C injection, Heilongjiang Gerun Pharmaceutical Co.
    , Ltd.
    , Sinopharm H20058721
    .

    [3] Drug information: vitamin C for injection, CSPC Ouyi Pharmaceutical Co.
    , Ltd.
    , Sinopharm H20053380
    .

    [4] Drug information: vitamin C chewable tablets, Changchun Dirui Pharmaceutical Co.
    , Ltd.
    , Sinopharm H22025676
    .

    [5] Drug information: vitamin C effervescent tablets, Bayer Healthcare Co.
    , Ltd.
    , Sinopharm H20056946, 2017/06/05
    .

    [6] Drug information: Vitamin C tablets, Northeast Pharmaceutical Group Shenyang First Pharmaceutical Co.
    , Ltd.
    , Sinopharm H21020713
    .

    [7] Drug information: vitamin C pills, Jilin Yatai Yong'an Tang Pharmaceutical Co.
    , Ltd.
    , Sinopharm H22020684
    .


    Click "Read Original" for more dry medications

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.