echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Digestive System Information > The new strain "XBB" is prone to diarrhea? Don't blindly hoard smearstones! The right thing to do is...

    The new strain "XBB" is prone to diarrhea? Don't blindly hoard smearstones! The right thing to do is...

    • Last Update: 2023-02-03
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    *For medical professionals only, montmorillonite


    is not preferred
     

    Written by | Dedicated pediatrician


    In the past two days, a hot search news has rushed to the headlines: "The new new crown variant XBB.
    1.
    5 is coming, specifically attacking the body's gastrointestinal tract and can cause diarrhea in children"
    .
    As a result, many parents began to stock up on the drug "montmorillonite scatter", and for a time, the montmorillonite scatter in major pharmacies was snapped up
    .


    In fact, children infected with the new crown virus mainly cause upper respiratory tract symptoms, some may involve the gastrointestinal tract, causing vomiting, diarrhea and other digestive symptoms, but at present, for the treatment of children's diarrhea disease, there is no specific treatment drug clinically, mainly symptomatic supportive treatment, so parents do not have to stock up on drugs and prepare drugs
    too much.


    Here, the author shares with parents the relevant knowledge
    of childhood diarrhea according to the current expert summary and relevant guidelines for childhood diarrhea.



    1.
    Will the new crown variant XBB cause diarrhea?


    The new crown variant XBB belongs to the new variant branch of Omicron and has not yet become the dominant strain
    in China at this stage.


    Although some children infected with the new crown virus can cause vomiting, diarrhea and other digestive symptoms, there is no clear evidence that the new crown variant XBB is more likely to invade the digestive system, so parents do not need to panic and hoard medicine
    .


    2.
    Children infected with the new coronavirus cause gastrointestinal symptoms

    , what are the possible clinical manifestations?


    1.
    Diarrhea manifestations
    such as increased frequency of stool and changes in stool characteristics (loose watery stools).

    2.
    Vomiting, abdominal pain, bloating, decreased
    appetite.

    3.
    Different degrees of dehydration
    .

    4.
    Electrolyte and acid-base balance disorders
    .

    5.
    Systemic symptoms
    such as fever, irritability, malaise, lethargy, coma, and shock.


    3.
    How to divide the dehydration of children's diarrhea disease clinically?


    Clinically, according to the percentage of water loss to body weight, the degree of dehydration is divided into mild, moderate and severe dehydration, and the manifestations of various degrees of dehydration are shown in Table 1
    .
    Determining the degree of dehydration can help guide the clinician's next treatment plan
    .

    Table 1 Indexing of dehydration

    4.
    After diarrhea in children,

    Is montmorillonite treatment preferred?


    For the treatment of children's diarrhea, many parents believe that diarrhea should be stopped in time, so most parents will choose to first give their children oral montmorillonite antidiarrheal treatment, in fact, this practice is wrong, antidiarrheal drugs due to inhibition of the child's gastrointestinal motility, will increase bacterial reproduction and toxin absorption, and is not conducive to the recovery
    of the disease.

    Although montmorillonite itself is an intestinal mucosal adsorbent, it can indeed play a role in adsorbing pathogens and toxins, but the current literature has a relatively low
    level of evidence for recommending montmorillonite powder for the treatment of acute diarrhea in children.
    Therefore, the treatment of infectious diarrhea in children should not be the drug of choice for montmorillonite powder, but should be after
    fluid replacement, correction of electrolyte abnormalities, diet therapy, etc.


    V.
    After children are infected with the new coronavirus,

    How should diarrhea be treated?


    1.
    Oral rehydration solution

    Dehydration may occur in children with diarrhoea, so fluid replacement is essential in children with diarrhoea, and oral rehydration salts III (ORS) are preferred in children without severe vomiting and mild to moderate dehydration III) to rehydrate, but newborns should be used
    with caution.

    For the prevention of dehydration, oral administration of enough ORS should be given to prevent dehydration from the beginning of diarrhea in the child, and a certain amount of fluid should be supplemented after each loose stool until the diarrhea stops, the specific amount of supplementation is 50ml for <6 months, 100ml for 6 months ~ 2 years old, 150ml for 2 ~ 10 years old, and how much can be drunk > 10 years old
    .

    For the treatment of mild and moderate dehydration, the dosage of ORS (ml) = body weight (kg) × (50~75), take it within 4 hours, evaluate the dehydration after 4 hours, and select the appropriate treatment plan
    .
    2.
    Intestinal microecological preparations

    Intestinal microecological preparations such as probiotics help restore the ecological balance of intestinal flora, inhibit the colonization and invasion of pathogenic bacteria, thereby controlling diarrhea, and clinically can choose microecological preparations
    containing bifidobacteria, Bacillus licheniformis, Saccharomyces boulardii and so on.

    3.
    Diet therapy

    Proper feeding is advocated, rather than fasting, and infants can continue to breastfeed
    .
    Because children with diarrhea often have secondary lactase deficiency, milk feeding can be temporarily stopped, and legumes, starchy foods can be changed to beans, starchy foods, or replaced with lactose formula feeding, but the time is generally not more than 2 weeks, and the fed food should follow the principle
    of less to more, from dilute to thick and easy to digest.
    In addition, children with vomiting can also be fed with small and frequent meals, that is, reduce the amount of food eaten per meal and increase the number of
    meals.

    4.
    Zinc supplementation therapy

    Zinc supplementation in children with diarrhea can shorten the duration
    of diarrhoea.
    For children with acute diarrhea over 6 months, 20mg of elemental zinc is given daily, and children under 6 months are given 10mg of elemental zinc per day, and the course of treatment is 10~14 days
    .

    5.
    It is forbidden to use antidiarrheal agents

    Antidiarrheal agents, such as loperbutol, are strictly contraindicated in children with diarrhea because they can inhibit gastrointestinal motility, increase bacterial reproduction, and toxin absorption
    .

    6.
    Avoid
    the abuse of antibiotics Antibiotic antibiotics are only suitable for children with bacterial intestinal infection, for diarrhea caused by new coronavirus infection, because it is a viral infection, the use of antibiotics will not bring benefits, on the contrary, the abuse of antibiotics may cause intestinal flora, causing antibiotic-related diarrhea, aggravating the symptoms
    of diarrhea.


    6.
    What are the occurrences of diarrhoeal diseases in children,

    Do parents need to take their child to the hospital immediately?


    1.
    Severe vomiting, diarrhea, obvious decrease in appetite, refusal to eat
    .

    2.
    Severe abdominal distention
    .

    3.
    Moderate or above dehydration manifestations
    such as mental malaise, obvious depression of anterior fontanelle, obvious dry skin, few or no tears when crying, significantly reduced urine output or anuria.

    4.
    Diarrhea lasts for a long time
    .

    5.
    Diarrhea with convulsive seizures
    .
    References:[1] Gastroenterology Group, Pediatrics Branch of Chinese Medical Association, Editorial Board of Chinese Journal of Pediatrics.
    Clinical practice guidelines for acute infectious diarrhoeal disease in children in China[J].
    Chinese Journal of Pediatrics, 2016, 54(7):483-488
    Fan Juan, Li Maojun, Wu Qing, et al.
    Diagnosis and management of infectious diarrhea in children——"2017 American Society of Infectious Diseases Clinical Practice Guidelines for the Diagnosis and Treatment of Infectious Diarrhea"[J].
    Chinese Journal of Practical Pediatrics, 2019, 34(15):1121-1126
    [3] Gui Yonghao, Xue Xindong.
    Pediatrics (3rd edition)[M].
    People's Medical Publishing House, 2016:178-187
    The web version of the doctor's website is online, please scan the QR code below or click to read the original article,
    you can browse more pediatric information 👇👇👇 without downloading



    Responsible editor: Xiang Yu


    *The "medical community" strives to publish content professionally and reliably, but does not make any commitment to the accuracy of the content; Relevant parties are requested to check
    separately when adopting or using it as a basis for decision-making.
    ↓↓↓Click "Read Original" to learn more clinical skills

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.