The new system simulates the most critical processes of early development of human embryos

BEIJING, Sept. 11 (Xinhua Zhang Mengran) Nature magazine published a stem cell field research results: a successful simulation of human embryos bed after the key processes of the system came out, help to enhance our understanding of the early development of human embryos, also does not involve the biological ethics related to human embryo research, because the system is in a strictly controlled environment, the use of human pluripotent stem cells.
Research on early embryo development after bed has been limited by the failure of cell culture methods to meet the best standards, the "14-day principle" (bioethics guidelines prohibit the use of human embryos cultured after fertilization for more than 14 days). The "14-day principle" has been carefully consulted and discussed by policy researchers, who believe that the embryo will begin to form a "line" when it develops to 14 days, a structure that allows the embryo to begin to possess some individual characteristics, which can raise ethical questions.
previously, pluripotent stem cells in humans and mice (cell types that can differentiate into specializations) have been used to simulate embryonic development behind a bed, but the success rate of such systems in reproducing critical developmental events has been limited.
Jianping Fu and colleagues at the University of Michigan at Ann Arbor demonstrated a controlled environment for the development of human omnichanta stem cells that improve the efficiency and repeatability of synthetic model systems. The team developed a microflow device consisting of three channels for placing cell-embedded materials, loading stem cells, and transporting factors that stimulate stem cell differentiation.
researchers were able to control the differentiation of stem cells in early human embryos toward major cell linees, producing synthetic embryo-like sacs. These sacs lack the specific cell types that produce living embryos. At the same time, they identified specific cell types that drive key events in embryonic development.