The new technology of artemisinin large-scale green production passed the result appraisal

On November 29, the "new process of artemisinin large-scale green production" jointly completed by the Institute of process engineering of the Chinese Academy of Sciences, Yuzhou Tianyuan Biotechnology Co., Ltd and the Institute of modern physics of the Chinese Academy of Sciences passed the scientific and technological achievements appraisal organized by the China Federation of petroleum and chemical industries Lin Guoqiang, academician of the Chinese Academy of Sciences and researcher of the Shanghai Institute of organic chemistry of the Chinese Academy of Sciences, served as the chairman of the meeting, Zhu Xiaoxin, researcher of the Institute of traditional Chinese medicine of the Chinese Academy of Sciences, and Ye Yang, researcher of the Shanghai Institute of medicine of the Chinese Academy of Sciences, served as the vice chairmen The appraisal committee agreed that the process has independent intellectual property rights, strong innovation, leading international level and broad application prospects Artemisinin is the most effective malaria treatment drug recommended by the World Health Organization (who) According to the appraisal committee, in view of the difficulties in large-scale production of artemisinin, the process engineering institute has developed a new process of countercurrent circulation enhanced solid-liquid mixing and mass transfer, high-efficiency extraction, thin-film evaporation decompression concentration, proposed a new process of extraction crystallization coupling purification enhanced by additives, conquered the key technologies of selective extraction and low-temperature crystallization regulation of product quality, and realized the whole system Mass energy coupling integration According to Jiang Hongge, deputy general manager of Yuzhou Tianyuan Biotechnology Co., Ltd., the company's 60 ton / young artemisinin production unit has realized safe and stable operation, and the quality of each batch of products is stable, meeting the national standards This achievement has formed a large-scale green production technology system of artemisinin, greatly reducing solvent loss and production cost, and improving product quality One belt, one road, and the other one, it provides a technological support for the extensive application of artemisinin medicinal products, and provides an important carrier for the "going out" policy It opens up a new way of economic and social benefits, which is in line with the strategic need of green upgrading of China's chemical pharmaceutical industry After the appraisal meeting, Zhengzhou branch of Process Engineering Institute and Henan Tianyuan Industrial Development Group held the unveiling ceremony of jointly building the "artemisinin extraction and biomass utilization Joint Laboratory" The two sides will further carry out scientific and technological cooperation, tackle the key problems of green technology, accelerate the pace of production, learning and research, promote the transfer and transformation of achievements, and continuously explore green technology innovation and sustainable development.