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The production process of 3-[(2-bromo-3-pyridinyl)oxy]-6-chloropyridazine is a multi-step process that involves various chemical reactions and purification steps.
The starting materials for the production of this compound are 2-bromo-3-pyridine, hydrogen chloride, and potassium hydroxide.
The final product is a white powder that is used as a ligand in the catalytic process of hydroformylation.
Step 1: Synthesis of 2-bromo-3-pyridine
The first step in the production of 3-[(2-bromo-3-pyridinyl)oxy]-6-chloropyridazine is the synthesis of 2-bromo-3-pyridine.
This can be achieved by the reaction of 3-pyridine with hydrogen bromide in the presence of a solvent such as acetonitrile.
The reaction is exothermic and requires careful monitoring to avoid excessive heating.
Step 2: Synthesis of 3-[(2-bromo-3-pyridinyl)oxy]-6-chloropyridazine
Once 2-bromo-3-pyridine has been synthesized, the next step is to convert it into 3-[(2-bromo-3-pyridinyl)oxy]-6-chloropyridazine.
This is achieved by the addition of hydrogen chloride and potassium hydroxide to 2-bromo-3-pyridine in the presence of a solvent such as ether or hexane.
The reaction is highly exothermic and requires careful monitoring to avoid excessive heating.
Step 3: Purification
After the reaction is complete, the product is purified by recrystallization in a solvent such as ethanol or hexane.
This step removes any impurities that may have been introduced during the synthesis process.
Step 4: Characterization
Once the product has been purified, it is characterized to determine its chemical properties.
This is achieved by performing various tests such as melting point, boiling point, density, and spectroscopy.
The results of these tests are used to confirm the identity of the product.
In conclusion, the production process of 3-[(2-bromo-3-pyridinyl)oxy]-6-chloropyridazine involves the synthesis of 2-bromo-3-pyridine, the addition of hydrogen chloride and potassium hydroxide, purification by recrystallization, and characterization to determine the chemical properties of the final product.
This compound is used as a ligand in the catalytic process of hydroformylation and is an important component in the chemical industry.