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    Home > Active Ingredient News > Drugs Articles > The Production Process of (+)-3-Carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy

    The Production Process of (+)-3-Carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy

    • Last Update: 2023-04-26
    • Source: Internet
    • Author: User
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    (+)-3-Carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy is a compound that is widely used in the pharmaceutical industry as an intermediate for the synthesis of various drugs.
    The production process of this compound involves several steps, which are carried out in a chemical plant equipped with state-of-the-art equipment and technology.


    The first step in the production process is the synthesis of the starting material, which is a mixture of aromatic amines and aldehydes.
    This is achieved by a reaction between aniline, which is an aromatic amine, and acetaldehyde, which is an aldehyde, in the presence of a catalyst such as aluminum chloride.
    The reaction is exothermic, and it is carried out under controlled conditions to ensure maximum yield.


    The next step is the reduction of the nitro group of the aromatic amine to the amine group by a reducing agent such as lithium aluminum hydride (LiAlH4).
    This is followed by the N-methylation of the resulting amine by methyl iodide in the presence of a base such as sodium hydride.


    The next step is the condensation of the resulting N-methylated amine with another N-methylated amine in the presence of a strong acid such as sulfuric acid.
    This results in the formation of a substituted urea, which is then hydrolyzed to yield the desired compound, (+)-3-carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy.


    The final step in the production process is the purification of the compound, which is achieved by crystallization, chromatography, or other methods.
    The purified compound is then packaged and shipped to pharmaceutical companies for use in the synthesis of drugs.


    The production process of (+)-3-carboxy-2,2,5,5-tetramethylpyrrolidinyl-1-oxy is a complex process that involves several steps, which are carried out in a controlled manner to ensure maximum yield and purity of the final product.
    The compound is widely used in the pharmaceutical industry as an intermediate for the synthesis of various drugs, and its production process is an important aspect of the pharmaceutical industry.


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