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The 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) is an important intermediate in the production of various pharmaceuticals, agrochemicals, and other chemical products.
The production process of this compound involves several steps, including the synthesis of the starting materials, the reaction process, and the purification and isolation of the product.
This article will discuss the production process of 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) in the chemical industry.
Step 1: Synthesis of Starting Materials
The synthesis of 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) requires the use of several starting materials, including pyrimidine-5-carboxaldehyde, 2-(1,1-dimethylethyl)benzimidazole-5-carboxaldehyde, and sodium hydroxide.
The pyrimidine-5-carboxaldehyde is synthesized by the reaction of pyrimidine-5-carboxylic acid with sodium hydroxide, while the 2-(1,1-dimethylethyl)benzimidazole-5-carboxaldehyde is synthesized by the reaction of 2-(1,1-dimethylethyl)benzimidazole with sodium hydroxide.
The synthesis of these starting materials involves several steps, including the purification and isolation of the intermediate products.
Step 2: The Reaction Process
The synthesis of 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) involves the reaction of pyrimidine-5-carboxaldehyde, 2-(1,1-dimethylethyl)benzimidazole-5-carboxaldehyde with each other in the presence of a suitable solvent and a catalyst.
The reaction process involves several steps, including the mixing of the starting materials, the addition of the catalyst, and the heating of the mixture to a suitable temperature.
The reaction process is carried out under controlled conditions to ensure the highest possible yield of the product.
Step 3: Purification and Isolation of the Product
After the completion of the reaction process, the product is separated and purified from the reaction mixture using a suitable method.
The most common methods used for the purification and isolation of 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) include crystallization, chromatography, and filtration.
The purified product is then dried and weighed to determine the yield of the product.
In conclusion, the production process of 5-pyrimidinecarboxaldehyde, 2-(1,1-dimethylethyl)- (9CI) involves the synthesis of starting materials, the reaction process, and the purification and isolation of the product.
The production process is carried out under controlled conditions to ensure the highest possible yield of the product.
The chemical industry relies on the production of this compound for the production of various pharmaceuticals, agrochemicals, and other chemical products.
The use of this compound in the production of these chemical products is expected to increase in the coming years due to the growing demand for these products in various industries.