The Production Process of Ethyl-(5-fluoro-pyrimidin-2-yl)-amine

Ethyl-(5-fluoro-pyrimidin-2-yl)-amine is a chemical compound that is commonly used in various industrial and commercial applications.
It is also known as 2-(5-fluoro-pyrimidin-2-yl)-ethylamine or CAS No 156597-88-8.
This compound is produced through a multi-step process that involves several chemical reactions and purification steps.

The production process of ethyl-(5-fluoro-pyrimidin-2-yl)-amine can be broken down into the following stages:

1. Synthesis of 2-chloro-5-fluoro-pyrimidine: This compound is synthesized by reacting 2-fluoro-pyrimidine with chloroform and hydrogen chloride in the presence of a catalyst.
   
2. Hydrolysis of 2-chloro-5-fluoro-pyrimidine: The resulting 2-chloro-5-fluoro-pyrimidine is then treated with water and a strong acid catalyst to produce 2-(5-fluoro-pyrimidin-2-yl)-ethylamine.
   
3. Purification of the resulting product: The product obtained from the previous step is then purified using various techniques such as distillation, crystallization, and chromatography to remove any impurities and improve its purity.
   
4. Hydrogenation of the product: The purified product is then treated with hydrogen gas and a metal catalyst to reduce the nitrogen atom to an amine group.
   
5. Purification of the resulting product: The product obtained from the previous step is then purified using the same techniques used in the previous step to remove any impurities and improve its purity.
   
6. Crystallization of the product: The final product is then crystallized from a suitable solvent to obtain pure ethyl-(5-fluoro-pyrimidin-2-yl)-amine.
   

The entire production process is carried out under strict quality control measures to ensure that the final product meets the required purity and quality standards.
The purity of the final product is typically determined using various analytical techniques such as melting point analysis, thin-layer chromatography, and nuclear magnetic resonance spectroscopy.

Ethyl-(5-fluoro-pyrimidin-2-yl)-amine is widely used in various industrial and commercial applications.
It is commonly used as an intermediate in the production of various chemicals, pharmaceuticals, and agrochemicals.
It is also used as a ligand in coordination compounds and as a building block for the synthesis of heterocyclic compounds.
The compound has good solubility in solvents such as water, ethanol, and methanol, and it is also practically insoluble in ether and benzene.

In conclusion, the production process of ethyl-(5-fluoro-pyrimidin-2-yl)-amine involves several chemical reactions and purification steps.
The entire production process is carried out under strict quality control measures to ensure that the final product meets the required purity and quality standards.
The compound is widely used in various industrial and commercial applications and has good solubility in several solvents.