The prospect of experimental mRNA AIDS vaccine is promising

Science and Technology Daily, Beijing, December 9th (Reporter Zhang Mengran) Scientists at the National Institute of Allergy and Infectious Diseases (NIAID) said that an mRNA-based experimental HIV vaccine shows promise in mice and non-human primates

The experimental vaccine works similarly to the mRNA new coronavirus vaccine, but does not carry the mRNA instructions of the coronavirus spike protein, but provides coding instructions to produce two key HIV proteins-Env and Gag

The researchers reported that in the experiment, two injections of the mRNA vaccine to form the VLP induced neutralizing antibodies in all animals

The research team then tested the Env-Gag VLP mRNA vaccine in rhesus monkeys

Starting from the 60th week, the immunized and non-immunized rhesus monkey control groups were exposed to SIV through the rectal mucosa every week

Editor-in-chief

Despite nearly four years of efforts by scientists around the world, an effective vaccine to prevent HIV is still an elusive goal