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A national study published in Nature Medicine SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland showed that among women who gave birth within 28 days of being diagnosed with COVID-19, The prolonged perinatal mortality rate was 22.
6 per 1000 births, compared with the Scottish baseline of 5.
6 per 1000 births
.
The findings also showed that serious complications known to be associated with COVID-19 during pregnancy — including severe hospitalization and perinatal death — occurred at significantly higher rates among unvaccinated women at diagnosis than among vaccinated women
.
Pregnant women do not appear to be more susceptible to SARS-CoV-2 infection than non-pregnant women, but they are at higher risk for severe illness
.
However, data on vaccination against COVID-19 during pregnancy and infection with COVID-19 have been lacking
.
To address this question, Sarah Stock at the Usher Institute at the University of Edinburgh, UK, and colleagues analysed data collected from the Scottish Pregnancy COVID-19 Study, a national cohort study of all people living in Women who became pregnant on or after March 1, 2020, and cross-correlated with COVID-19 infection and COVID-19 vaccination data
.
The database ultimately tracked 144,546 pregnancies in 130,875 women between March 1, 2020, and October 31, 2021
.
The authors found that the vaccine coverage rate of pregnant women (32% of women who gave birth in October 2021) was much lower than that of the average woman aged 18-44 (77%), and that the monthly vaccination rate of pregnant women increased from August 2021 onwards month down
.
Prolonged perinatal mortality in vaccinated women was similar to baseline extended perinatal mortality in undiagnosed women
.
Seventy-seven percent of Covid-19 infections, 98% of severe hospital admissions, and all neonatal deaths in the study occurred in pregnant women who had not been vaccinated against Covid-19 at the time of diagnosis
.
The authors concluded that women should be vaccinated during pregnancy to avoid adverse maternal and neonatal outcomes associated with COVID-19
.
The authors emphasize that continued efforts are needed to increase vaccination rates among pregnant women
.
Pregnant women infected with the new coronavirus and vaccination
.
Source: Stock et al.
©NatureNat Med | doi: 10.
1038/s41591-021-01666-2
6 per 1000 births, compared with the Scottish baseline of 5.
6 per 1000 births
.
The findings also showed that serious complications known to be associated with COVID-19 during pregnancy — including severe hospitalization and perinatal death — occurred at significantly higher rates among unvaccinated women at diagnosis than among vaccinated women
.
Pregnant women do not appear to be more susceptible to SARS-CoV-2 infection than non-pregnant women, but they are at higher risk for severe illness
.
However, data on vaccination against COVID-19 during pregnancy and infection with COVID-19 have been lacking
.
To address this question, Sarah Stock at the Usher Institute at the University of Edinburgh, UK, and colleagues analysed data collected from the Scottish Pregnancy COVID-19 Study, a national cohort study of all people living in Women who became pregnant on or after March 1, 2020, and cross-correlated with COVID-19 infection and COVID-19 vaccination data
.
The database ultimately tracked 144,546 pregnancies in 130,875 women between March 1, 2020, and October 31, 2021
.
The authors found that the vaccine coverage rate of pregnant women (32% of women who gave birth in October 2021) was much lower than that of the average woman aged 18-44 (77%), and that the monthly vaccination rate of pregnant women increased from August 2021 onwards month down
.
Prolonged perinatal mortality in vaccinated women was similar to baseline extended perinatal mortality in undiagnosed women
.
Seventy-seven percent of Covid-19 infections, 98% of severe hospital admissions, and all neonatal deaths in the study occurred in pregnant women who had not been vaccinated against Covid-19 at the time of diagnosis
.
The authors concluded that women should be vaccinated during pregnancy to avoid adverse maternal and neonatal outcomes associated with COVID-19
.
The authors emphasize that continued efforts are needed to increase vaccination rates among pregnant women
.
Pregnant women infected with the new coronavirus and vaccination
.
Source: Stock et al.
©NatureNat Med | doi: 10.
1038/s41591-021-01666-2
