The research team of Wu Qinghua from Yangtze University fully revealed the distribution characteristics of DON biomarkers in different populations around the world

Recently, the research group of Wu Qinghua from Yangtze University published an article in Trends in Food Science & Technology— Biomarkers of Deoxynivalenol (DON) and its Modified Form DON-3-glucoside (DON-3G) in Humans", fully revealing that DON in grains is different in the world.

Regional characteristics

The human exploration of DON biomarkers began with the study in the French population ten years ago.

age

In adults, DON-15-GlcA is the main biomarker in urine.

DON-15-GlcA was detected in urine samples of Belgian children (3-12 years old), and DON-3-GlcA was detected in 77% of urine samples.

In the elderly, DON-GlcA is the main biomarker in urine.

Pregnant woman

During pregnancy, the fetus is also poisoned by food contaminated by the mother’s toxins.

Eating habits

China is mainly located in temperate regions.

Vegetarians have a higher risk of exposure to DON, and they consume more vegetables and grains in their daily lives.

gender

At present, there is no specific report on the human DON biomarker between male and female.

Concealed Toxin DON-3G

Compared with DON, there are few reports on human DON-3G biomarkers.

Conclusion and Outlook

The conjugated products DON-15-GlcA, DON-3-GlcA, and free DON are human DON biomarkers.

About the Author

Professor Wu Qinghua

Wu Qinghua, born in 1981, is a professor and doctoral supervisor; a visiting professor at the University of Hradec Kralove in the Czech Republic.

Deng Ying, master student

Deng Ying, female, born in 1999, is an undergraduate student majoring in food quality and safety at Yangtze University.

(The article "Biomarkers of deoxynivalenol (DON) and its modified form DON-3-glucoside (DON-3G) in humans" was published in Trends in Food Science & Technology in April 2021.