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The role of DNA methylation in regulating the development and maturation of fruits

 Last Update: 2022-09-27
 Source: Internet
 Author: User

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journal neuroscience research

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Recently, scientists from Shanxi Datong University and Chongqing University found that SlCMT4 plays an important role in the development of tomatoes, encodes a DNA methyltransferase

Using the CRISPR/Cas9 system, SlCMT4 (Solyc08g005400.

CRISPR/Cas9-mediated knockout SlCMT4 induced the expression of two pollen-specific genes PMEI and PRALF, inhibiting pollen wall development and pollen tube elongation, resulting in pollen irregularities and defects

Whole genome bisulfite sequencing (WGBS) showed that knocking out SlCMT4 reduced genome-wide cytosine methylation, particularly CHH methylation

"This study clarifies that SlCMT4 can collaborate

In summary, this study shows that SlCMT4 is necessary for the normal development of the vegetative and reproductive organs of

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