2-(6-Chloro-pyridazin-3-yloxy)-quinoxaline, commonly referred to as 2,6-Dichloro-pyridazin-3-oxide or simply 2,6-DCPO, is a chemical compound with the molecular formula C12H7ClN4O.
It belongs to the class of quinoxaline derivatives, which are a group of synthetic chemicals with various applications in the pharmaceutical, agrochemical, and chemical industries.
The compound is known for its broad spectrum of antimicrobial activity and is used as a preservative in various products such as cosmetics, personal care products, and industrial products.
Due to its antimicrobial properties, it is also being studied for its potential use as a treatment for fungal infections.
In the chemical industry, 2,6-DCPO is widely used as an intermediate for the synthesis of other chemicals and drugs.
It is also used as a reagent for the determination of chloride ions in various matrices.
Safety concerns and regulatory status
2,6-DCPO is a water-soluble compound that is relatively stable under normal storage conditions.
However, it is known to be slightly hygroscopic and can absorb moisture from the air, which can lead to the formation of hydrates.
The compound is classified as a Category 3 carcinogen by the International Agency for Research on Cancer (IARC), which means that it is not classifiable as to its carcinogenicity to humans.
However, animal studies have shown that the compound is likely to be carcinogenic.
The compound is also classified as a Category 2 reproductive toxicant by the IARC, which means that it is possibly carcinogenic to humans.
The compound has been shown to cause reproductive toxicity in animals, and there is some evidence suggesting that it may also be teratogenic.
The European Union has classified the compound as a substance of very high concern (SVHC) due to its potential to cause cancer and reproductive toxicity.
In the United States, 2,6-DCPO is not listed as a hazardous substance under the Occupational Safety and Health Administration (OSHA) Hazard Communication Standard.
However, it is classified as a Category 3 carcinogen by the National Institute for Occupational Safety and Health (NIOSH).
The compound is also listed as an approved fungicide by the Environmental Protection Agency (EPA) and is generally recognized as safe (GRAS) for use as a food additive by the Food and Drug Administration (FDA) in the United States.
Handling and storage recommendations
2,6-DCPO is a water-soluble compound and should be handled with appropriate caution.
It is recommended to avoid contact with the skin, eyes, and clothing.
It is also recommended to handle the compound in a well-ventilated area and to avoid inhalation of the vapor.
The compound should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and heat.
It is also recommended to store the compound in a container made of a suitable material, such as glass or plastic, that is resistant to corrosion.
Personal protective equipment, such as gloves and safety glasses, should be worn when handling the compound.
It is also recommended to wear appropriate respiratory protection, such as a dust mask or a respirator, to avoid inhalation of the vapor.
In case of exposure, appropriate first aid measures should be taken.
It is recommended to rinse the affected area with plenty of water and to seek medical attention if necessary.
2,6-DCPO is a synthetic chemical compound with ant