echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > The Shanghai Jiao Tong University Nature publication found that the SENP1-Sirt3 axis regulates the formation and activity of memory T cells

    The Shanghai Jiao Tong University Nature publication found that the SENP1-Sirt3 axis regulates the formation and activity of memory T cells

    • Last Update: 2021-07-28
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

     The dynamic changes of mitochondria and metabolic reprogramming play a key regulatory role in the fate determination of CD8+ T cells


    Cheng Jinke’s research group at Shanghai Jiaotong University School of Medicine recently published a research paper entitled Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development in Nature Communications.


    In terms of molecular mechanism, a new mechanism was discovered that SENP1-Sirt3 axis regulates OPA1 shearing and promotes mitochondrial inner membrane fusion


    This study reveals the molecular mechanism of the immune microenvironment through regulating T cell mitochondrial metabolism, affecting the formation of memory T cells and the ability of anti-tumor


    Dr.


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.