The significance of the first gene interaction map.

The meaning of the first gene interaction map: When two or more mutations in a gene interact and produce unexpected characteristics, gene interaction occurs.
, for example, two not-fatal genetic mutations that combine can lead to cell death.
because some of them are more likely than others to influence other mutations, the process of causing genes and their mutations to interact with each other is complex, and researchers at the University of Toronto have created the world's first map of how genes interact in cells.
University of Toronto have created the world's first map of how genes interact in cells.
study, published in Science, offers new ideas for studying how genes cause disease.
cell schematic is shown above.
genetic sequencing project provides an unprecedented perspective on genetic variation.
but our ability to predict characteristics from these genetic information is more challenging because many genes are not necessary for survival.
a study of yeast a decade ago found that only one in five genes is necessary for survival.
, the study has also found that only a small percentage of genes are necessary for human cells, and that most of them act as "buffers" to protect cells from genetic mutations and environmental stress.
makes it difficult to identify which genes are related to a particular manifestation, especially if they interact.
"Our ability to interpret genetic information and predict genetic performance is still limited, in large part because there are many buffer genes that make most individual cell genes not necessary for life," the authors said.
" researchers used yeast genes to build their genetic networks, and genes with similar gene interaction properties used a global network connection.
in this network, genes that exhibit similar traits are closer to each other, while genes with less similarity are farther apart.
a reference guide on how to map gene interactions," said Michael Costanzo, an assistant researcher in the study.
can now confirm which properties should be looked at when looking for highly interconnected genes in the human genetic network that have the potential to cause genetic diseases.
" DNA (deoxybonucleic acid) is a molecule that carries genetic information in all forms of life, including viruses.
diagram begins to explain how thousands of genes coordinate to make cell life work smoothly.
findings allow people to better understand genetic diseases.
genetic interactions may explain a significant portion of undiscovered genes associated with human diseases.
.