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    Home > Active Ingredient News > Antitumor Therapy > The simple "increase in lung texture" is actually cancer behind it?

    The simple "increase in lung texture" is actually cancer behind it?

    • Last Update: 2022-09-07
    • Source: Internet
    • Author: User
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    Increased lung texture and thickening are clinically common, often without practical significance, and are common in patients with smoking and chronic bronchitis! However, even if the common lung texture increases and thickens, sometimes it will hide a very serious disease, that is, pulmonary hemangioma embolism (lung tumor embolism).


    Case 1

    79-year-old male, shortness of breath in January after sexually aggravated activities, coughing up yellow sputum for 2 weeks


    The outer hospital was diagnosed with "acute bronchitis", treated with clindamycin + cough medicine, sputum production, and dyspnea worsened


    Past history: Smoking for 30 years (e.


    Physical examination: breath sounds are normal, no signs of


    Laboratory tests: spirometry is not performed


    Complementary examination: fibronchoscopy does not reveal endobronchial lesions


    Chest enhancement CT scan did not reveal pulmonary embolism, but lung windows showed disturbances, increased, and thickening of lung texture (arrow below), and mediastinal windows showed hilar and mediastinal lymphadenopathy


    Figure 1

    Handling: Perfect inspection


    Increased lung texture is often due to thickening of the bronchial wall, dilation of pulmonary blood vessels, combined with hilar and mediastinal lymphadenopathy, and no lung mass, suggesting metastatic lung cancer and pulmonary hemangioma thrombosis


    Upper and lower gastrointestinal endoscopy shows only mild sinusitis


    Ultrasound bronchoscopy-guided needle aspiration biopsy of mediastinal lymph nodes, cytology reveals tumor cells characterized by adenocarcinoma, suggesting metastases


    Right-middle lobe lung biopsy confirms adenocarcinoma within muscle-on-the-arterioles and lymphatic vessels, with neither endometrial hyperplasia nor pulmonary artery thrombosis


    CT of the abdomen shows enlarged prostate and destruction


    The patient's dyspnea gradually worsens, and the lung lesions progress


    After the treatment, the lung texture is clear and smooth, and the symptoms are completely relieved


    Figure 2

    Case 2

    A 60-year-old woman with vaginal bleeding
    .
    Advanced cervical cancer is diagnosed with invasion of the uterine body, bilateral parauterine, vagina, rectum, and bladder, with liver metastases
    .

    After one week, patients develop progressive dyspnea, cyanosis, tachycardia (105 bpm), and tachypnea (30 bpm).

    Oxygen saturation is 80 to 85%, blood pressure and body temperature are normal
    .
    No abnormalities
    were found on auscultation of both lungs.
    Blood gas analysis showed a partial pressure of 54.
    9 mmHg for oxygen and 21.
    8 mmHg
    for carbon dioxide.

    Laboratory tests show elevated D-dimer, C-reactive protein, white blood cell count, and creatinine levels
    .

    I attached the original text, is how to feel that foreign doctors are so free, creatinine is elevated, this patient can also take it to enhance CT
    .

    Chest enhancement CT did not detect pulmonary embolism (Figure 3)!

    Figure 3

    Without pneumothorax, without pulmonary embolism, without lung infection, without airway stenosis, why does the patient have trouble breathing?

    Careful masters have found that the thickening of the lung texture around the lungs (arrow below) dilates for the pulmonary arterioles, indicating pulmonary tumor embolism! Isn't this clinically very common?

    Figure 4

    Her condition rapidly deteriorated on the fourth day after admission, and she died from respiratory failure.

    What's the situation?

    Autopsy of the remains shows a tumor emboli in the pulmonary artery (arrow below), and the lung parenchyma is not invaded!

    Figure 5

    Diffuse tumor embolism is found in pulmonary arterioles (below
    ).
    The arteriole wall has a normal structure
    .
    Most vascular linings are normal and no blood clot formation
    is observed.

    Figure 6

    Case 3: Typical peripheral intrapulmonary artery tumor suppository

    The figure below is a typical pulmonary intraarterial tumor embolus, chest CT flat scan of the lung window shows that the tumor embolus metastasizes along the pulmonary artery, and the pulmonary artery expands
    .

    Figure 7

    Case 4: Atypical manifestations of pulmonary aneurysm suppositories

    Some pulmonary aneurysms appear as patchy shadows that are extremely difficult
    to diagnose.

    A 36-year-old breast cancer patient was admitted to the hospital
    for shortness of breath.
    No pulmonary embolism was found in the pulmonary artery CTA, and the flat scan of the lung window is shown in the figure
    below.
    But the patient soon developed respiratory failure, shock, and then sudden death
    .
    Autopsy of the remains shows extensive lymphatic and vascular tumor embolism
    .

    Figure 8

    Case 5: Pulmonary aneurysm suppositories resemble pulmonary thrombosis

    Many lung tumor embolisms are not fundamentally different from the lung thrombuses we usually see in imaging, and it is difficult to distinguish
    .

    The image below shows tumors in other areas that have metastasized to the pulmonary blood vessels and are indistinguishable from
    pulmonary thrombosis.

    Figure 9

    Case 6: Pulmonary endovascular lymphoma

    Pulmonary endovascular lymphoma, which may also lead to tumor-associated increased and thickening of lung texture (pictured below), but is often accompanied by a frosted glass shadow, which can also present as nodules, solid shadows, or similar to interstitial pneumonia
    .

    Figure 10

    postscript

    Lung texture disorder, increase, thickening, many times there is no special clinical significance, but any imaging abnormalities must be combined with clinical comprehensive analysis to find the huge information
    hidden in it.

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