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    Home > Active Ingredient News > Drugs Articles > The size of the new coronavirus is too large, which may be the reason why the vaccine antibody is ineffective

    The size of the new coronavirus is too large, which may be the reason why the vaccine antibody is ineffective

    • Last Update: 2021-06-30
    • Source: Internet
    • Author: User
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    Coronavirus is a single-stranded positive-sense RNA virus with a thick envelope.
    Its genetic material is the largest of all RNA viruses and is an important pathogen for many domestic animal, pet, and human diseases
    .


    It can cause various acute and chronic diseases


    The size of the new coronavirus is twice the size of the original SARS virus

    The previously measured and calculated size of the new coronavirus is about 120 to 250 nanometers
    .


    Nowadays, the new coronavirus is still constantly mutating and combining, and it is constantly recombining new genetic components to generate new surface proteins, which may cause it to become larger and larger


    Also, the hepatitis B virus that we often talk about, its actual size is only about 40 nanometers
    .


    In contrast, the new coronavirus is 3 to 7 times the hepatitis B virus


    The spherical corolla of the new coronavirus may cause a larger volume

    The most notable feature of the new coronavirus is its corolla.
    This corolla is due to the raised protein it expresses.
    This protein actually increases the volume of the original new coronavirus in disguise, especially the virus and the body fluids of the human body.
    When in contact, the outer surface area of ​​the spherical shape increases significantly
    .


    What's more, the new coronavirus does not exist as an individual, but is usually a collective activity.


    What is the neutralizing antibody of the new coronavirus? Such as IgM and IgG

           Generally, we say that antibodies refer to antibodies to xx proteins or molecules, but when we hear about antibodies to the new coronavirus, we always add the word "neutralization"
    .


    What does this mean? This is because everyone has a common misunderstanding.


           Common neutralizing antibodies igM and igG and other antibodies, first look at the difference between them
    .


    Immunoglobulin M (IgM) and immunoglobulin G (IgG) are antibodies or immunoglobulins produced by the immune system to fight infection and destroy antigens


           Also, the basic structure of antibodies is the same
    .


    Simply put, an antibody consists of two heavy chains (50 KD each) and two light chains (25 KD each), which are connected by disulfide bonds to form a Y-shaped structure (150 KD)


           summary

           In short, if the antibody is specifically penetrating, then the antibody will penetrate and split the virus like a bullet
    .


    However, for the current type of new coronavirus with strong self-protection, the only way for antibodies is to wrap the body of the virus; but when the human body produces insufficient antibodies or the new coronavirus is exposed to the outside world in excess, the vaccine is produced.


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