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The reporter learned from the Hefei Research Institute of the Chinese Academy of Sciences that researcher Wang Junfeng from the strong magnetic field center of the academy and Professor Zhang Teng of Fuzhou University cooperated to prepare nano-scale borate bioactive glass based on the steady-state strong magnetic field experimental device, which not only greatly reduced the borate biological The biotoxicity of glass improves the biocompatibility of glass, and significantly promotes the effect of borate bioglass on skin repair, which is expected to become the next generation of skin wound repair dressings
Skin damage not only affects the physiological functions of the human body and even endangers life and safety, the field of skin tissue repair has become a hot spot in biomedical research
However, borate bioglass releases a large amount of alkaline ions, and the explosive release of these ions will change the acid-base environment of the tissue surrounding the glass material, thereby inhibiting cell proliferation
In this study, researchers innovatively used the flow-relative melting method to prepare micron-scale borate bioglass for in vitro pretreatment, and finally obtained nanoscale borate bioglass with an amorphous layer on the surface
The results of in vitro degradation experiments, cell experiments and animal experiments show that the slow-released boron calcium and other elements of nano-scale borate bioglass not only effectively accelerate the migration of cells in the wound, but also up-regulate the expression of vascular-related growth factors in the wound