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According to a study published online by Nature, Spread of a SARS-CoV-2 variant through Europe in the summer of 2020, the restoration of travel in Europe starting in June 2020 may have contributed to a new variant of SARS-CoV-2 It spreads quickly in the summer
.
This study points out that this new variant 20E (EU1), which is believed to have appeared in Spain, has been introduced to European countries hundreds of times by summer travelers
.
Although the mutation does not show increased transmission, these findings indicate how travel can promote mutation frequency and emphasize the importance of genome monitoring and prevention and control strategies when resuming travel
.
At present, the new coronavirus is almost tracked in real time through viral genome sequencing, and this method can also detect the emergence of new mutations
.
Emma Hodcroft of the University of Bern, Switzerland, and colleagues report that a new mutation was detected in Spain in the early summer of 2020, which later spread in Europe
.
This mutation is called 20E (EU1), and there is a mutation in the virus spike protein region (the structure that mediates the virus into the host cell)
.
However, this mutation does not seem to have a significant effect on transmission
.
In order to determine how this variant became the main source of the new crown epidemic in Europe in the fall of 2020, the author traced its evolutionary history (physical development)
.
Their analysis showed that 20E (EU1) was most popular in Spain between July and August, but by the end of August, the variant was found in many European countries, including Belgium, Switzerland, France, Denmark, the United Kingdom, Germany, Latvia, Sweden, Norway and Italy
.
The phylogenetic tree shows that the mutation has been exported from Spain many times, and the pattern of entering other countries is consistent with the prediction of travel data
.
Many EU countries resumed travel in mid-June and reached a peak in July and August, which coincided with the peak of the Spanish 20E (EU1) epidemic
.
Therefore, the author proposes that the recurrence of cases in many European countries is partly due to insufficient international travel and quarantine
.
The authors concluded that as travel resumes, it is necessary to improve prevention and control strategies and reduce the risk of transmission of variant strains in order to help countries maintain a low level of new coronavirus transmission
.
The evolutionary history of the new crown epidemic in European countries at the end of November
.
Source: Hodcroft et al.
©NatureNature | doi: 10.
1038/s41586-021-03677-y
.
This study points out that this new variant 20E (EU1), which is believed to have appeared in Spain, has been introduced to European countries hundreds of times by summer travelers
.
Although the mutation does not show increased transmission, these findings indicate how travel can promote mutation frequency and emphasize the importance of genome monitoring and prevention and control strategies when resuming travel
.
At present, the new coronavirus is almost tracked in real time through viral genome sequencing, and this method can also detect the emergence of new mutations
.
Emma Hodcroft of the University of Bern, Switzerland, and colleagues report that a new mutation was detected in Spain in the early summer of 2020, which later spread in Europe
.
This mutation is called 20E (EU1), and there is a mutation in the virus spike protein region (the structure that mediates the virus into the host cell)
.
However, this mutation does not seem to have a significant effect on transmission
.
In order to determine how this variant became the main source of the new crown epidemic in Europe in the fall of 2020, the author traced its evolutionary history (physical development)
.
Their analysis showed that 20E (EU1) was most popular in Spain between July and August, but by the end of August, the variant was found in many European countries, including Belgium, Switzerland, France, Denmark, the United Kingdom, Germany, Latvia, Sweden, Norway and Italy
.
The phylogenetic tree shows that the mutation has been exported from Spain many times, and the pattern of entering other countries is consistent with the prediction of travel data
.
Many EU countries resumed travel in mid-June and reached a peak in July and August, which coincided with the peak of the Spanish 20E (EU1) epidemic
.
Therefore, the author proposes that the recurrence of cases in many European countries is partly due to insufficient international travel and quarantine
.
The authors concluded that as travel resumes, it is necessary to improve prevention and control strategies and reduce the risk of transmission of variant strains in order to help countries maintain a low level of new coronavirus transmission
.
The evolutionary history of the new crown epidemic in European countries at the end of November
.
Source: Hodcroft et al.
©NatureNature | doi: 10.
1038/s41586-021-03677-y
