The study found new targets for coffee efficacy: antioxidant and inhibition of kidney cancer.

China News Agency, Kunming, October 15th, reporters learned from Yunnan Agricultural University, recently, the university professor Sheng Jun scientific research team found
caffeine
health function of two new targets, revealing the
caffe coffee
antoxidant
and anti-kidney cancer molecular system, for the widespread use of caffeine provides a scientific basis.
the study of caffeine health function has not been able to clarify the target of its efficacy for a long time, making the molecular efficacy of coffee health effects slow down.
Shengjun research team through molecular interoperability technology research found that caffeine can be directly combined with an important deacetylization modification enzyme (SIRT3) in the cell mitochondrials, elophine directly in the cell mitochondrial SIRT3 binding, enhance its biological activity, can liven up peroxide dismplification enzyme 2 (SOD2), remove ultraviolet radiation in the mitochondrials produced by the molecular mechanism of the oxidizing free base effect. The results show that caffeine effectively improves the skin damage induced by UV radiation and provides scientific basis for the development of caffeine for UV skin care products.
In addition, the study also found that caffeine can be associated with intracellular glucose metabolism enzymes (glucose-6-phosphate dehydrogenase, G6PDH) binding to inhibit its bioenzyme activity, regulate redox steady state, thereby inhibiting the development of kidney cancer, revealing the molecular mechanism of caffeine inhibition of kidney cancer. The results provide clues to the use of caffeine in the prevention and treatment of kidney cancer.
research was published recently in the international journal Fro
In Developmental and Cell Biology.
.