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a drug for osteoporosis is expected to be used to treat hair loss problems such as shedding, according to a new study by the University of New Development.
some of the patients received hair transplants and donated useless scalp follicles. Experiments by Nathan Hawkeshaw's team at the University of Manchester's Centre for Dermatology have shown that the drug WAY-316606, which treats osteoporosis, has the effect of stimulating hair follicle development.
is mostly seen in men. In addition to hair transplantation, only "Medinol" and "non-nastamine" are commonly used, but the efficacy is often less than ideal, with some side effects.
previous studies have found that cyclosporine-A, an immunosuppressant used to treat transplant rejection and autoimmune diseases, promotes hair growth, but is not directly used to treat hair loss due to serious side effects.
Hawkshaw team conducted a full-gene expression analysis of the hair follicles treated with cyclosporine-A and found that the drug inhibited the expression of the secretion-type curly-related protein 1, which inhibits the development of many tissues, including hair follicles.
They later discovered that the drug "WAY-316606" for osteoporosis had the same mechanism as "cyclosporine-A", both of which were antagonists against "secretion-type curl-related protein 1", thus lifting the "molecular gate" of the body's inhibitory hair growth.
the drug is expected to have the same effect as cyclosporine-A, but without side effects, the researchers said. They also need to conduct further clinical trials to determine whether the drug or similar compounds can be used safely and effectively to treat hair loss. (Source: Xinhua Zhouzhou)