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2-(6-Chloro-3-pyridazinyl)-2-(2-pyridinyl)acetonitrile is an organic compound with a unique chemical structure and diverse range of potential applications.
The synthetic routes for this compound can be broadly categorized into two types: direct synthesis and indirect synthesis.
Direct Synthesis Route
The direct synthesis route involves the synthesis of the target compound in a single step starting from the individual reactants.
The most common direct synthesis route for 2-(6-chloro-3-pyridazinyl)-2-(2-pyridinyl)acetonitrile is through the reaction of 2-chloro-3-pyridine with 2-(2-pyridinyl)acetone in the presence of a strong acid catalyst, such as sulfuric acid.
This reaction is exothermic and requires careful handling and monitoring to avoid unwanted side reactions.
Indirect Synthesis Route
The indirect synthesis route involves the synthesis of intermediate compounds that are then transformed into the target compound through a series of chemical reactions.
One common indirect synthesis route involves the synthesis of 2-chloro-3-pyridine via the reaction of 3-pyridinecarboxaldehyde with chloroform in the presence of a Lewis acid catalyst, such as aluminum chloride.
The resulting 2-chloro-3-pyridine is then reacted with 2-(2-pyridiny