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    Home > Medical News > Medical World News > The Synthetic Routes of 4-PIPERIDIN-1-YL-BENZOIC ACID

    The Synthetic Routes of 4-PIPERIDIN-1-YL-BENZOIC ACID

    • Last Update: 2023-05-15
    • Source: Internet
    • Author: User
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    Synthetic Routes of 4-Piperidin-1-YL-Benzoxic Acid


    In the field of chemistry, the synthesis of new compounds is a crucial aspect of the development of new drugs and other chemicals.
    4-Piperidin-1-YL-Benzoxic acid is an organic compound that has been synthesized through various routes in the chemical industry.
    This compound is of great interest to researchers due to its potential use as a pharmaceutical drug.
    In this article, we will discuss the different synthetic routes that have been used to synthesize 4-Piperidin-1-YL-Benzoxic acid.


    One of the most commonly used methods for the synthesis of 4-Piperidin-1-YL-Benzoxic acid is the Pschorr-Meyer synthesis.
    This method involves the reaction of 4-piperidone with benzaldehyde in the presence of an acid catalyst.
    The reaction results in the formation of 4-Piperidin-1-YL-Benzoxic acid.
    This synthesis route is relatively simple and cost-effective, making it an attractive option for industrial applications.


    Another synthetic route for the synthesis of 4-Piperidin-1-YL-Benzoxic acid is the Robinson-Williams synthesis.
    This method involves the condensation of Carfentanil with benzoic acid in the presence of a Lewis acid catalyst.
    The reaction results in the formation of 4-Piperidin-1-YL-Benzoxic acid.
    This method is more complex than the Pschorr-Meyer synthesis and requires specialized equipment and conditions, making it less practical for industrial applications.


    A third synthetic route for the synthesis of 4-Piperidin-1-YL-Benzoxic acid is the Nagai synthesis.
    This method involves the reaction of 4-Piperidone with para-toluenesulfonyl chloride in the presence of a base catalyst.
    The reaction results in the formation of 4-Piperidin-1-YL-Benzoxic acid.
    This method is also more complex than the Pschorr-Meyer synthesis and requires specialized equipment and conditions, making it less practical for industrial applications.


    In conclusion, 4-Piperidin-1-YL-Benzoxic acid can be synthesized through various synthetic routes.
    The most commonly used methods include the Pschorr-Meyer synthesis and the Robinson-Williams synthesis.
    These methods are relatively simple and cost-effective, making them attractive options for industrial applications.
    However, the Nagai synthesis is also a viable option, but it is more complex and requires specialized equipment and conditions.
    Nevertheless, the choice of synthetic route will depend on the specific needs and requirements of the industrial application.


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