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    Home > Medical News > Medical Research Articles > The Synthetic Routes of Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1)

    The Synthetic Routes of Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1)

    • Last Update: 2023-05-17
    • Source: Internet
    • Author: User
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    Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl], compd.
    with 1,1′-sulfinylbis[methane] (1:1) is a new and innovative synthetic drug that has shown promise in the treatment of a variety of diseases.
    This compound is of particular interest to researchers and scientists in the field of chemical synthesis and drug development due to its complex structure and unique properties.


    One of the most challenging aspects of synthesizing N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl] compd.
    with 1,1′-sulfinylbis[methane] (1:1) has been the development of an efficient and reliable synthesis route.
    This has been a difficult task due to the complex and challenging nature of the compound itself.


    There are a number of different synthetic routes that have been explored in the development of N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl] compd.
    with 1,1′-sulfinylbis[methane] (1:1).
    Some of these routes include:


    1. The Sandmeyer Reaction: This reaction involves the condensation of an acyl halide with a phenylamine in the presence of a strong aprotic acid catalyst.
      This reaction has been used to synthesize the central portion of the compound, including the acyl halide and the phenylamine moieties.
    2. The Grignard Reaction: This reaction involves the formation of a Grignard reagent, which is then used in a subsequent reaction step to introduce the desired functional group.
      This reaction has been used to synthesize the para-methoxybenzylamine moiety of the compound.
    3. The Wolff-Kishner Reduction: This reaction involves the reduction of a carbonyl group using a reducing agent such as hydrogen gas or a metal reducer.
      This reaction has been used to reduce the carbonyl group in the para-methoxybenzylamine moiety of the compound.
    4. The Suzuki Reaction: This reaction involves the coupling of a boronic acid with a phenylboronic acid in the presence of a palladium catalyst.
      This reaction has been used to introduce the boronic acid moiety of the compound, which is then coupled with the Grignard reagent synthesized via the Grignard reaction.

    These are just a few of the many different synthetic routes that have been explored in the development of N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl] compd.
    with 1,1′-sulfinylbis[methane] (


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