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    Home > Active Ingredient News > Drugs Articles > The Synthetic Routes of tert-Butylaminoethyl methacrylate

    The Synthetic Routes of tert-Butylaminoethyl methacrylate

    • Last Update: 2023-05-01
    • Source: Internet
    • Author: User
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    tert-Butylaminoethyl methacrylate (BAEMA) is an important monomer used in the production of various polymers and copolymers.
    It is widely used in the chemical industry as a building block for the synthesis of various polymers and is an essential component in the production of polymeric membranes, adhesives, and coatings.

    The synthetic routes of BAEMA can be broadly classified into two categories: conventional and modern.
    The conventional routes involve the use of traditional methods such as the reaction of methyl methacrylate with ammonia, followed by hydrolysis of the resulting methacrylamide to yield BAEMA.
    This method, however, suffers from several drawbacks such as low yield, high cost, and poor selectivity.

    The modern synthetic routes of BAEMA, on the other hand, involve the use of more advanced techniques such as the use of transition metal catalysts and electrochemical methods.
    These methods are more efficient and cost-effective than the conventional methods and offer several advantages such as higher yields, better selectivity, and more environmentally friendly processes.

    One of the most commonly used modern synthetic routes of BAEMA is the use of transition metal catalysts such as palladium and rhodium.
    This method involves the use of a Pd/C or Rh/C catalyst in the presence of a strong polar solvent such as DMF or DMAc.
    The reaction conditions, such as temperature and pressure, are carefully controlled to ensure maximum yield and selectivity.

    Another modern synthetic route of BAEMA is the electrochemical method.
    This method involves the use of an electrochemical cell with a DC or AC voltage applied to a solution of methyl methacrylate and ammonia in a polar solvent such as DMF.
    The electrochemical reduction of nitrogen gas to ammonia in the presence of the electrodes leads to the formation of BAEMA.
    This method is highly efficient and offers several advantages over the conventional methods, such as higher yield and better selectivity.

    In addition to the above methods, there are several other modern synthetic routes of BAEMA that have been developed in recent years.
    One such method is the use of ionic liquids as catalysts in the reaction of methyl methacrylate and ammonia.
    This method has the advantage of using mild conditions and is more environmentally friendly than traditional methods.

    Another method is the use of microwave irradiation in the synthesis of BAEMA.
    This method involves the use of microwaves to accelerate the reaction and reduce the reaction time, leading to higher yields and better selectivity.

    In conclusion, the synthetic routes of tert-Butylaminoethyl methacrylate are an important aspect of the chemical industry and have undergone significant changes in recent years with the advent of more advanced techniques.
    The modern methods, such as the use of transition metal catalysts and electrochemical methods, offer several advantages over the conventional methods and have revolutionized the production of BAEMA.
    As the industry continues to evolve, it is likely that even more efficient and cost-effective methods will be developed to meet the increasing demand for this important monomer.

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