The United States accelerates the reduction of new coronavirus-targeted infections.

Reuters reports that U.S. government scientists are developing a new coronavirus to deliberately infect volunteers to speed up the development of the new corona vaccine.
This work is still early, and even if this so-called viral challenge trial is actually conducted, it will not replace the normal Phase III clinical trials of several new coronavirus currently under way, but if these clinical failures do, they may require such ethically questionable trials."
several major drug technology technology technology developing vaccines have said they will consider the option if needed, and NIAID says it is considering the technical feasibility and ethics of such trials.
Drug source analysis Even though many parts of the world, including the United States, is still a large-scale epidemic, but through natural infection accumulation of enough patients to see the efficacy of the vaccine still need more than 30,000 volunteers, three months, and directly to volunteers spray a pot of new crown as long as one or two hundred people can, time is greatly shortened.
can be used in small-scale epidemics or viral infections with reliable drug control, the new crown does not yet have a highly effective drug.
the other trials were definitely young people who were less at risk, and the difference between the immune response and the high-risk older population was questionable, as was the transformation into the real world.
of course, the biggest problem with such experiments is ethical.
Although more than 160,000 people have died in the U.S. today, and volunteers have a very low mortality rate from the new crown itself, not to mention a variant that reduces life, it is ethically questionable to appoint someone at a specified time and place to bear this even small risk of death.
this virus challenge test is to keep increasing the dose until you get infected, with the aim of artificially inducing the disease.
many volunteers in every country are willing to sacrifice for this, it is necessary to maintain basic ethical norms as a society.
why save soldier Ryan's life could sacrifice seven equally priceless lives? Because "Maybe saving Private Ryan is the one decent thing we did in this war".
the heavy pressure on Raine to sacrifice seven people in his lifetime, today's survey showed that one-third of Americans said the new crown vaccine would not be available even if it went on the market.
the first criterion for pharmaceutical use is First do no harm.
Although there is a risk that any new drug will be used for the first time, and that the first phase of TGN1412 clinically sending all six volunteers to the ICU has occurred, the new drug usually requires a large amount of preclinical data to control the very low risk and terminate if there are side effects."
is well known for the time-consuming and labor-consuming development of new drugs, and one of the main objectives and responsibilities is to ensure the safety of clinical trial participants.
many people don't understand why a single drug can sell for $1,000 because picking out a compound from countless compounds that are harmless to patients and improves the disease requires a lot of time-consuming and costly work.
if compounds were screened directly into the human body, the uncertainty caused by the differences between many people and experimental animal species would disappear.
is not ethical because it brings too much uncertainty to volunteers, and it's not a time of life or death.
more than a decade ago, manufacturers used so-called Phase 0 clinical, ultra-low-dose drugs to obtain human data to find a balance between safety and species differences, but for a variety of reasons it was not widespread.
in addition to the uncertainty that patients bring, manufacturers also face uncertainty if they screen drugs at the clinical stage.
a few days ago we said that if we could save the success rate and cost of the development of phase III clinical new drugs, the cost of screening drugs in the clinic would be much higher.
in the past few years, the tide of immunotherapy has left investors residing, even though most of the treatments and combination therapies that lack preclinical support have earned meth.
of course, the new crown is an extremely special case, no disease requires the U.S. government to come up with trillions of dollars to help, if ethics allow for the cost of clinical screening drugs are drizzle.
in addition, if the virus activity is reduced to low enough itself may be a vaccine, if can increase infectious even production, distribution are saved.
every bar is quickly immunized, and of course there is no precedent for this treatment.
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