The United States initially supports the provision of new crown booster injections for people with weakened immune systems. Will Fubitai become a booster injection in my country?

The United States has begun to consider for the immune vaccination crown new vaccine booster force poor people over the past week, the US average daily infection count reached the highest level since early May

Another reason is that the protective effect of certain vaccines may be weakened over time.

According to the Wall Street Journal, the Advisory Committee on Immunization Practices (ACIP) of the U.

As more and more evidence shows that compared with the general population, the new crown vaccine is less effective in people with weakened immune systems, thereby increasing their risk of infection and development of severe illness, so the committee is conducting the above-mentioned enhanced needle assessment

At present, many countries have begun to take action to vaccinate some people with booster shots

Anthony Fauci, a top US infectious disease official, said on Sunday that Americans with weakened immune systems may eventually need a booster shot of the new crown vaccine

Jay Butler, deputy director of the CDC's infectious disease prevention and control in the United States, previously believed that for those who have been fully vaccinated, the third dose of vaccine may bring a higher risk of adverse reactions

A spokesperson for the New Coronary Vaccine Team at the University of Oxford in the United Kingdom said that some mutant strains have evolved to avoid part of the human immune response, which means they can more easily infect people who have recovered from the new coronavirus or have been vaccinated

There is also a view that booster shots may be beneficial to the elderly or people with weakened immune systems, because their bodies may not have a strong enough immune response after the earlier vaccination, but there is still evidence to prove that they are given to these people.

Pfizer Pharmaceuticals Co.

According to the statement, data from a recent paper published in the British journal Nature showed that the test found that the human body had a higher level of neutralizing antibodies to the Delta strain after the second dose of Pfizer vaccine

According to data previously released by the Israeli Ministry of Health, the protective effect of Pfizer vaccine has declined 6 months after vaccination, but it still has a significant effect in preventing severe illness

With the increase in the number of people who have completed the two doses of vaccination, the British government has also begun to consider implementing the third dose booster plan as soon as possible

A preprinted paper published by the US "Social Science Research Network" not long ago stated that Oxford University researchers used AstraZeneca vaccine as the research object and found that the third dose of the vaccine can greatly enhance the immune response

In China, a person familiar with the matter said that in the future, Fosun Pharma’s mRNA new crown vaccine "Fubitai" is likely to be used as a booster in China and vaccinated free of charge
.
In June of this year, the University of Hong Kong announced a comparative study of vaccines.
It pointed out that people who received the BioNTech/Pfizer vaccine (the same vaccine for Fubitai) had a higher antibody response than those who received the China Kexing vaccine
.
Benjamin Cowling, a Hong Kong pandemic epidemiologist, said that the study also recommends that people who have been vaccinated with Kexing receive a third dose
.

Another study of the University of Hong Kong is a mixed vaccination study
.
Hong Fanyi, a clinical professor in the Department of Internal Medicine of the University of Hong Kong, said in mid-June that the University of Hong Kong recruited about 50 people to participate in the mixed vaccination study of the new crown vaccine.
For the time being, the safety was good and no serious adverse reactions were seen.
Next month, analysis of antibody production will begin
.
Kong Fanyi once said that the antibody level caused by mixed vaccination may be higher than that of single vaccination
.

A study published in July by researchers from the University of Oxford in the United Kingdom showed that people who received one dose of AstraZeneca vaccine and then a dose of BioNTech/Pfizer vaccine four weeks later produced more than those who received two doses of AstraZeneca vaccine.
Of antibodies
.
Even if the order of mixed vaccination is reversed, it is still better than two doses of AstraZeneca vaccine
.
Research participants who received both doses of the BioNTech/Pfizer vaccine produced the most antibodies
.
830 volunteers over the age of 50 participated in this mixed vaccination study
.

Researchers at Saarland University in Germany found that people who received the AstraZeneca vaccine first and then the BioNTech/Pfizer vaccine had a stronger immune response than those who received two doses of the same vaccine
.
However, the research has not yet been peer reviewed
.

The World Health Organization still advises against mixed vaccination so far because there is not enough data for follow-up evaluation
.
However, in Germany, mixed vaccination is as recognized as vaccination of the same vaccine
.
Germany follows the guidelines of the Paul-Ehrlich-Institut and the vaccination committee
.
The most well-known example of mixed vaccination in Germany is German Chancellor Merkel
.
She received the first dose of AstraZeneca vaccine and the second dose was Modena
.