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2,5-Dibromopyrimidine is an organic compound that is widely used in the chemical industry.
It is a white crystalline solid that is soluble in water and organic solvents.
The compound is synthesized by several methods, including the reaction of pyrimidine-5-carboxylic acid with bromic acid, and the electrophilic substitution of chlorine in 2,5-dichloropyrimidine with bromine.
Upstream Products
The upstream products of 2,5-dibromopyrimidine are the raw materials that are used to synthesize the compound.
These materials include pyrimidine-5-carboxylic acid, bromic acid, and 2,5-dichloropyrimidine.
Pyrimidine-5-carboxylic acid is synthesized by the reaction of pyrimidine with carbon dioxide in the presence of an acid catalyst, such as sulfuric acid.
Bromic acid is synthesized by the reaction of bromine with water, or by the oxidation of hydrobromic acid.
2,5-dichloropyrimidine is synthesized by the chlorination of pyrimidine-5-carboxylic acid.
Downstream Products
The downstream products of 2,5-dibromopyrimidine are the chemicals and products that are derived from the compound.
These materials include herbicides, insecticides, and pharmaceuticals.
The most common downstream product of 2,5-dibromopyrimidine is 2,5-dibromofluoroaniline, which is used as an intermediate in the synthesis of several herbicides, including atrazine and propazine.
Herbicides
2,5-Dibromopyrimidine is a key intermediate in the synthesis of several herbicides, which are used to control weeds in crops.
Atrazine is one of the most commonly used herbicides in the world, and it is synthesized from 2,5-dibromopyrimidine.
Atrazine is a selective herbicide that controls weeds without harming crops.
It is widely used in corn, sorghum, and wheat production.
Propazine is another herbicide that is synthesized from 2,5-dibromopyrimidine.
It is used to control weeds in turf, and it is also used in crop production.
Insecticides
2,5-Dibromopyrimidine is also used in the synthesis of insecticides, which are used to control pests in crops and other environments.
One of the most common insecticides made from 2,5-dibromopyrimidine is dichloro-S-triazine, which is used to control insects in crops such as rice and soybeans.
Pharmaceuticals
2,5-Dibromopyrimidine is used in the synthesis of several medications, including antibiotics and anti-cancer drugs.
One of the most widely used antibiotics made from 2,5-dibromopyrimidine is the antibiotic trimethoprim, which is used to treat bacterial infections.
Manufacturing Process
The manufacturing process for 2,5-dibromopyrimidine involves several steps, including synthesis, purification, and isolation of the final product.
The synthesis of 2,5-dibromopyrimidine typically involves the reaction of pyrimidine-5-carboxylic acid with bromic acid, or the electrophilic substitution of chlorine in 2,5-dichloropyrimidine with bromine.
The purification and